L23 - autonomic nervous system Flashcards

1
Q

afferent neurones

A

sensory input from periphery to CNS

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2
Q

efferent neurones

A

output from CNS to periphery (somatic or autonomic), causes skeletal muscles to move

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3
Q

what does the ANS do?

A

provides input to tissue that’s not under voluntary control (smooth & cardiac muscle and glandular tissue)

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4
Q

2 branches of ANS

A

sympathetic & parasympathetic
(have opposite actions but not equal)

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5
Q

sympathetic nervous system

A

fight or flight

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6
Q

parasympathetic

A

rest and digest

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7
Q

somatic motor fibre

A

neurone that goes from spinal cord to skeletal muscle to enable us to have voluntary control of it (neurone releases ACh)

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8
Q

ganglian

A

collection of cell bodies

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9
Q

sympathetic branch of ANS has what type of ganglion?

A

short pre ganglion fibre and long post ganglionic fibre

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10
Q

parasympathetic branch has what type of ganglion?

A

long pre ganglion fibre and short post ganglionic fibre

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11
Q

what do the short pre ganglionic neurones tend to project to from the sympathetic nervous system?

A

paravertebral sympathetic chain

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12
Q

what do the long post ganglionic neurones in the sympathetic nervous system send?

A

long axonal projections where the synapse ends on the target organ

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13
Q

where does output from CNS from parasympathetic ns come to?

A

cranial nerves

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14
Q

sympathetic division of ANS

A
  • fight or flight mode
  • sensors perceive you are in dangerous situation, tell the brain
  • pupils dilate: better peripheral vision, see out corner of eye better
  • inhibition of saliva and tears: saliva is part of digestion to not use up energy
  • oxygenated blood sent to skeletal muscle
  • airways dilate, relax airways in lungs so we can breath deeper
  • accelerated heartbeat pumps blood around body faster
  • liver stores glycogen which is metabolised into glucose (liver can still produce glucose without glycogen)
  • intestines shut down
  • bladder relaxes so can store more urine
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15
Q

parasympathetic divison

A
  • comes from vagus nerve
  • constriction of pupil
  • stimulation of saliva to digest food for nutrients
  • lungs constrict, no more heavy energy demands
  • stimulation of pancreas (insulin, enzymes etc)
  • heart slows
  • activation of rectum and bladder to use toilet
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16
Q

vagus nerve

A

provides output from brain to periphery to parasympathetic

17
Q

is chemical or electrical signal responsible for slowing heart down?

A

chemical (ACh is released from vagus nerve)

18
Q

somatic efferents NT and receptors in ANS

A

ACh acts on nicotinic receptors to stimulate skeletal muscle

19
Q

sympathetic NT and receptors in ANS

A

ACh acts on nicotinic receptors on post ganglionic, post ganglionic neurone releases noradrenaline which activates adrenergic receptors on heart, blood vessels

20
Q

parasympathetic NT and receptors in ANS

A

ACh acts on nicotinic receptors on post ganglionic, post ganglionic neurone releases ACH to act on muscarinin receptors on heart, smooth muscle, sweat glands

21
Q

adrenal medulla exception for sympathetic NT and receptors

A
  • one big long axon
  • only produces ACh to act on adrenal medulla
22
Q

what does sympathetic input do?

A
  • increase heart rate
  • dilate pupils
    -relax airways
23
Q

what are adrenoreceptors?

A

receptors that respond to adrenaline

24
Q

muscarinic receptors

A

respond to ACh

25
Q

what type of of receptors are adrenoreceptors and muscarinin receptors?

A

g protein coupled receptors

26
Q

G protein coupled receptors

A
  1. Gs-coupled: activates adenylate cyclase - leading to production of cAMP
  2. Gi/Go-coupled: inhibits adenylate cyclase, and affects ion channels
  3. Gq-coupled: activated phospholipase C - leading to production of IP3