L22

Question 1

What is the most important kinin?

Answer 1

bradykinin

Question 2

Which mediators act as neurotransmitters in the brain?

Answer 2

Vasoactive amines

Question 3

Which receptor is responsible for contraction of non-vascular smooth muscle?

Answer 3

H1

Question 4

Which receptor is responsible for allergy and vomiting?

Answer 4

H1

Question 5

Which receptor is responsible for gastric acid secretion?

Answer 5

H2

Question 6

Which receptor is responsible for feed-back inhibition?

Answer 6

H3

Question 7

What are examples of Eicosanoids?

Answer 7

PGs and LTs

Question 8

What are the 2 main enzymes involved in synthesis of eicosanoids?

Answer 8

COX and LOX

Question 9

What fatty acid is the precursor of eicosanoids?

Answer 9

Arachidonic acid

Question 10

Which enzyme is involved in synthesis of hydroperoxides and Leukotrienes?

Answer 10

Lipoxygenase (LOX)

Question 11

Which enzyme is responsible for synthesis of endoperoxides ?

Answer 11

COX

Question 12

which LT is a strong chemoattractant?

Answer 12

LTB4

Question 13

Which factor induces platelet aggregation?

Answer 13

PAF

Question 14

Which interleukins, along with TNF-a stimulate the liver to synthesize acute phase proteins?

Answer 14

IL-1, IL-6

Question 15

Which mediators promote expansion of neutrophil, eosinophil, and macrophage colonies in bone marrow?

Answer 15

Colony-stimulating factors