L2 - Why we Differ Flashcards
What is the Diathesis Stress Model?
- Biological factors + Environmental factors = Behavioural Trait & Phenotype
Study describing environmental factors with gender
- Babies climb a ramp
- Mothers were asked how successful they thought their child was going to be climbing
- Mothers of girls were less optimistic, thinking they would be worse
- Parents put an ability to their children, shaping them
Study describing biological factors with monkeys
- Monkeys given range of toys, both masc&fem
- male monkeys chose masc toys and vice versa
- Monkeys have not experienced toys, so chose based on genetic makeup, suggesting biological underpinning
How does Sex affect Individual Differences?
Affects:
- Intelligence, Personality, Emotion, Pain, Regional connectivity, Regional sizes & molecular biology
- Causes different diseases e.g colourblindess & ADHD is more prom in males
- EX: Water level test: to measure where the top of the water is in a half full glass when tilted toward the mouth, boys spatial ability is better
Difference between Heredity and Heritability
Heredity is transmission of traits from parents to offspring
Heritability is genetic variation between individuals in a population
How to use twins to work out variation
Use MZ twins and check concordance rates, do the same with DZ twins. If MZ rates are high, it has to be more genetic
Describe Epigenetics
- Things added to genetics
- Alters DNA
- Not genetic mutation
- Can be inherited
- Can be reversed
- Alters gene expression
- Genes are silenced, blocked, facilitated
What happened in the Dutch Winter Famine?
- Increased prevalence of CNS problems
- Babies in last trimester showed symptoms of schiz when mothers were suffering from malnutrition, showing reduced epigenetic markers after malnutrition.
- Env factors can cause epigenetic changes, affecting biological factors
What is a gene?
Region of DNA and sequence of nucleotides. One gene makes one protein
How to make a protein?
1) Transcription: DNA to mRNA
2) Translation: mRNA to protein
- Primary = Sequence of amino acids
- Secondary = Hydrogen bonds form to make either a alpha helix or beta pleated sheet
- Tertiary = other bonds form (Ionic, R-Groups, Hydrophilic etc.)
- Quaternary = Multiple subunits folding together
4 types of protein
- Enzyme
- Structural
- Neurotransmitter
- Receptor
How do genes cause disease?
- Faulty protein/receptor causes schiz
- Increasing/Decreasing neurotransmitter levels
- Extra genes = down syndrome
Describe Alzheimers Disease
From APP, PS1 and PS2 malfunction