L2 - Cartilage Histology - Articulate H Flashcards
Connective tissues are made up of what two general things? Which of the two is the major component?
- Cells
- Extracellular matrix
- ECM = major component
Extracellular matrix is composed of what two things that are secreted from the cells?
- Protein fibers
2. Ground substance
What 3 things make up protein fibers?
- Collagen fibers
- Reticular fibers
- Elastic fibers
What 3 things make up the unstructured hydrophilic ground substance?
- Glycosaminoglycans (GAGs)
- Proteoglycans
- Multiadhesive glycoproteins
What tissue gives rise to connective tissues? What is this tissues made of?
- Mesenchyme
2. Mesenchymal stem cells
What type of cell can give rise to endothelium, lipoblasts, fibroblasts, hematopoietic stem cells, mesothelium, osteoblasts, and chondroblasts?
Mesenchymal stem cells
What two cells are associated with cartilage and what are their roles?
Chondroblasts - Secrete ECM Chondrocytes -Secrete and maintain ECM
- What percentage of cartilage is ECM?
2. What is the ECM rich in? 3. What is the function?
- 95% volume
- Rich in GAG’s and proteoglycans
- Resilient to mechanical forces
What is the dense connective tissue that covers most cartilage?
Perichondrium
Cartilage has or doesn’t have blood vessels?
Doesn’t
_____ growth - by addition of new ECM to the existing surface - new chondroblasts
Appositional growth
_____ growth - by internal expansion; proliferation of chondrocytes and formation of isogeneous groups
Interstitial growth
What are the 3 types of cartilage?
- Hyaline cartilage
- Elastic cartilage
- Fibrocartilage
The most common type of cartilage in the human body is?
Hyaline cartilage
_____ cartilage’s ECM is largely made of water; it is found in the nose, larynx, and fetal bone models; it has perichondrium present; and appears bluish-white and translucent with basophilic staining.
Hyaline cartilage
Which type of cartilage is known as a shock absorber?
Hyaline cartilage