L17 - Pain

Question 1

DEFINITION PAIN

Answer 1

Pain = unpleasant sensory and emotional experienced associated with potential or actual tissue damage

Question 2

BPS model of pain

Answer 2

BPS:
- biological: tissue damage, inflammation, nerve injury.. = physical aspects of pain
- Psychological: emotions: anxiety, depression, cognitive processes…
- Social: cultural influences, social support, family, work, socioeconomic status..

Question 3

Definition of central sensitization

Answer 3

Central sensitization = neurological phenomenon in which nervous system becomes hyper-reactivity to pain
—> amplification of pain signals even in absence of major stimulation
—> lead to hypersensitivity: hyperalgesia and allodynia
—> associated to chronic condition like fibromyalgia and irritable bowel syndrome

Question 4

Neuroscience of pain (100 words)

Answer 4

Transduction
Transmission
Modulation
Perception