L16 - Brain Development Flashcards
What are the three regions that the rostral end of the neural tube develops into?
Forebrain
Midbrain
Hindbrain
What is another name for the forebrain that develops directly from the neural tube?
Prosencephalon
What is another name for the midbrain that develops directly from the neural tube?
Mesencephalon
What is another name for the hindbrain that develops directly from the neural tube?
Rhombencephalon
Which of the three regions of the developing brain do not divide any further?
Mesencephalon (Midbrain)
As the brain begins to develop in the embryo, what happens to the yolk sac?
Shrinks
Which two structures classify the neuroectoderm?
Neural crest cells
Neural Tube
How are flexures formed?
The folding that occurs with the expansion of the rostral end of the neural tube into the brain creates flexures.
What are the three flexures?
Cephalic
Cervical
Pontine
List the three important factors in determining the organisation of the brain regions.
Hox Genes
Fgf8
Retinoic Acid
What two regions does the forebrain further divide into?
Telencephalon
Diencephalon
What structure develops into the dorsal horn of the spinal cord?
Alar Plate
What structure develops into the ventral horn of the spinal cord?
Basal Plate
What is the most caudal part of the brain?
Hindbrain (Rhombencephalon)
What two regions does the rhombencephalon further get divided into?
Myelencephalon
Metencephalon
Which part of the hindbrain forms the medulla oblongata?
Myelencephalon