L15 Adrenoceptor agonists

Question 1

adrenoceptors for alpha-1,2 and beta-1,2,3

Answer 1

alpha-1: stimulate G protein of phospholipase C
alpha-2: inhibitory G protein of adenylate cyclase
beta-1,2,3: stimulate G protein of adenylate cyclase

Question 2

Adrenaline acts on which receptor?

Answer 2

a1=a2 b1=b2

Question 3

Noradrenaline acts on which receptor?

Answer 3

a1=a2 b1»b2

Question 4

Isoproterenol acts on which receptors?

Answer 4

b1=b2

Question 5

Dobutamine acts on which receptor?

Answer 5

b1»b2

Question 6

Salbutamol acts on which receptor?

Answer 6

b2»b1

Question 7

Which receptor acts on eyes? What is the effect of pupils?

Answer 7

• alpha-1
• pupils dilate/ mydriasis

Question 8

Which receptor acts on bronchial smooth muscle and what its effect?

Answer 8

• B2
• bronchodilation

Question 9

Which receptor acts on blood vessels of URT mucosa and what its effect?

Answer 9

• alpha receptor
• vasoconstriction

Question 10

Which receptor acts on smooth muscle of GIT and what its effect?

Answer 10

• a and b
• relaxation
• decrease GIT motility

Question 11

Which receptor acts on bladder detrusor and its effect?

Answer 11

• B2
• relaxation
• urinary retention

Question 12

Which receptor increase insulin secretion

Answer 12

• B

Question 13

Which receptor acts on lipolysis

Answer 13

• B3 receptor
• lipolysis

Question 14

Which receptor acts on glycogenolysis

Answer 14

• B2 and A1

Question 15

Which receptor stimulate renin secretion

Answer 15

• B1

Question 16

Which receptor provide amylase secretion

Answer 16

• B

Question 17

Which receptor inhibit renin secretion?

Answer 17

A2

Question 18

Which receptor decrease insulin secretion

Answer 18

A2