L12 Cholinomimetic agonists therapeutic applications Flashcards
1
Q
Drugs used to treat glaucoma
A
- direct agonist: pilocarpine, methacholine
- indirect agonist: physostigmine, echothiophate, demecarium
- alpha agonist: brimonidine, apraclonidine
- beta-blockers: timolol, betaxolol
2
Q
How glaucoma can be treated?
A
- contract ciliary body
- facilitate outflow of aq. humour
- decrease IOP
3
Q
Accommodative esotropia (abnormal alignment of eye)
A
- treat with cholinomimetic agonists
4
Q
Postoperative ileus (paralysis of the stomach or bowel after surgery)
A
PO bethanechol
SC/ PO neostigmine
5
Q
Atony of urinary bladder, urinary retention
A
SC bethanechol
SC/ PO neostigmine
6
Q
Dry mouth associated with Sjogren’s syndrome
A
PO pilocarpine
PO cevimeline
7
Q
NMJ - Myasthenia gravis
A
- can be treated by cholinesterase inhibitor (neostigmine, pyridostigmine)
- can be diagnosed by edrophonium
- symptoms: diarrhea, abdominal cramps, increased salivation,