L12 Cholinomimetic agonists therapeutic applications Flashcards

1
Q

Drugs used to treat glaucoma

A
  • direct agonist: pilocarpine, methacholine
  • indirect agonist: physostigmine, echothiophate, demecarium
  • alpha agonist: brimonidine, apraclonidine
  • beta-blockers: timolol, betaxolol
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2
Q

How glaucoma can be treated?

A
  • contract ciliary body
  • facilitate outflow of aq. humour
  • decrease IOP
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3
Q

Accommodative esotropia (abnormal alignment of eye)

A
  • treat with cholinomimetic agonists
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4
Q

Postoperative ileus (paralysis of the stomach or bowel after surgery)

A

PO bethanechol
SC/ PO neostigmine

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5
Q

Atony of urinary bladder, urinary retention

A

SC bethanechol
SC/ PO neostigmine

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6
Q

Dry mouth associated with Sjogren’s syndrome

A

PO pilocarpine
PO cevimeline

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7
Q

NMJ - Myasthenia gravis

A
  • can be treated by cholinesterase inhibitor (neostigmine, pyridostigmine)
  • can be diagnosed by edrophonium
  • symptoms: diarrhea, abdominal cramps, increased salivation,
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