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Anatomy🧠 > L12: Connective Tissue II (alyaa) > Flashcards

L12: Connective Tissue II (alyaa) Flashcards

1
Q

The three main types of CT fibers are:

A
  1. Collagen
  2. Reticular
  3. Elastic
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2
Q

Name each protein that make up the 3 main types of CT fibers?

A
  1. Collagen: protein collagen
  2. Reticular: protein collagen type III
  3. Elastic: elastin protein
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3
Q

True or false?

The three main types of CT fibers are composed of short, thick, protein monomers which are present in variable proportions in different CTs

A

FALSE

The three main types of CT fibers are composed of LONG, SLENDER, protein POLYMERS which are present in variable proportions in different CTs

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4
Q

What type of fibers do we find in the tendon?

A

Collagen fibers

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5
Q

What type of fibers will we find in the adrenal cortex?

A

Reticular fibers

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6
Q

What type of fiber will we find in the aortic wall?

A

Elastic lamellae

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7
Q

When it comes to the fibers in the aortic wall, we cannot say “elastic fibers” what do we call it instead?

A

Elastic lamellae

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8
Q

Main fiber type found in most supporting tissues?

A

Collagen fiber

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9
Q

Most abundant protein in the body?

A

Collagen fibers

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10
Q

True or false?

The most abundant protein in the body is elastin protein

A

False, it’s collagen fibers

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11
Q

Notable function of collagen fibers?

A

Provision of tensile strength

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12
Q

Color of fresh collagen fibers?

A

Fresh fibers are colorless, but when present in large
numbers, they cause the tissues in which they lie to
be white

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13
Q

Most abundant and widely distributed TYPE of collagen?

A

Type I Collagen

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14
Q

bones, dentin, tendons, dermis are all examples or where you would find…?

A

Collagen type 1

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15
Q

Describe the chain of Collagen type 1

A

2 of alpha chains are identical and 1 is different

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16
Q

Collagen type 2 is present mainly in?

A

Hyaline and elastic cartilages

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17
Q

True or false

Collagen type II are only in very thin fibril forms

A

True

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18
Q

Describe the chain in collagen type II

A

All 3 alpha chains are identical
(but different from those of other collagens)

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19
Q

Compare the difference between the alpha chains in collagen type I and type II?

A

TYPE I: 2 identical alpha chains and one is different

TYPE II: All 3 alpha chains are identical (but different from those of other collagens)

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20
Q

Which collagen type is usually associated with Collagen type I?

A

Collagen type III

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21
Q

What is a major collagenous component of Reticular
fibers ?

A

Collagen type 3

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22
Q

Which collagen type can co-polymerize with other types of collagen?

A

Collagen type 3

23
Q

Which of these collagens does not form fibrils or fibers?

1) Type I Collagen
2) Type IV Collagen
3) Type III Collagen

A

Type IV Collagen

24
Q

What does collagen type 4 make up?

A

basal lamina of epithelial & endothelial cells

25
Q

What does collagen type 4 NOT form?

A

fibrils or fibers

26
Q

The form of type 1 collagen

A

fibril, large banded fiber

27
Q

fibril, large banded fiber is the form of

A

Collagen type 1

28
Q

The form of type II collagen

A

fibril, small banded fiber

29
Q

fibril, small banded fiber is the form of?

A

Type II & III collagens

30
Q

Form of type III collagen?

A

fibril, small banded fiber

31
Q

Form of type IV collagen?

A

network, sheetlike

32
Q

Which collagens have a network form?

A

Type IV & VII Collagens

33
Q

Which collagen forms a sheetlike form?

A

Type IV collagen

34
Q

Type IV collagen is in thee form of?

A

network, sheetlike

35
Q

Which collagen is 90% of body collagen?

A

Collagen type I

36
Q

Which collagen makes up these tissues?
bone, skin, tendons, ligaments, cornea, internal organs

A

Type I collagen

37
Q

Which collagen makes up these tissues?
cartilage (hyaline and elastic)

A

Type II collagen

38
Q

Which collagen makes up these tissues?
internal organs (e.g., reticular fibers in lymph nodes, spleen, liver, blood vessels, skin)

A

Type III collagen

39
Q

Which collagen makes up the basal lamina (lamina densa)?

A

Type IV collagen

40
Q

What tissue does type VII collagen make up?

A

The tissue beneath the epithelia

41
Q

The synthesizing cells that make up type 1 Collagen

A

fibroblast, osteoblast

42
Q

The synthesizing cells that make up type II Collagen

A

Chondroblasts

43
Q

The synthesizing cells that make up type III Collagen

A

fibroblast, reticular cell, smooth muscle cell, hepatocyte

44
Q

The synthesizing cells that make up type IV Collagen?

A

Epithelial cell, muscle cell, schwann cells

45
Q

The synthesizing cells that make up type VII Collagen

A

Epidermal cells

46
Q

Type IV collagen forms a meshwork of what? AND what is that thing for?

A

A meshwork el procollagen for support 3 filtration of the basal lamina

47
Q

List the functions of Type IV and VII collagens in the basement membrane

A

Type IV collagen forms a meshwork of procollagen for support and
filtration in the basal lamina.

Type VII collagen anchors the basal lamina to the underlying type I and III collagens of lamina reticularis of the basement membrane

48
Q

Anchoring fibrils are made of…

Anchoring plaques are made of…

A

Anchoring fibrils: Type VII collagen

Anchoring plaques: Type IV collagen

49
Q

Collagen synthesis:

1) Collagen is produced by?

2) The principle AA that make up collagen are?

3) The protein unit is? Its definition?

A

1) Collagen is produced by:
fibroblast, chondroblasts, osteoblasts and odontoblasts.

2) The principle AA’s that make up collagen are:
Glycine 33%
Proline 12%
Hydroxyproline 10%.

3) The protein unit is:
tropocollagen, which is an elongated molecule polymerized to form collagen fibrils.

50
Q

Tropocollagen Molecules:

1) composition?
2) held together by?
3) Each complete turn of the helix spans distance of?
4) The length and width of each is?

A

1) Each molecule is composed of 3 subunit polypeptide α chains (can be same or different) intertwined in a right-handed triple helix.

2) Held together by hydrogen bonds.

3) Each complete turn of the helix spans distance of 8.6 nm.

4) Length: 280 nm
Width: 1.5 nm.

51
Q

1) α chains of tropocollagen consist of what amino acids?

2) And every 3rd AA must be ….. to fit in triple helix?

A
52
Q

1) Collagen fibers consist of bundles of threadlike fibrils bound together by?

2) fibrils are composed of arrays of?

*bonus q: label this
A
53
Q

Collagen Fibers by EM Characteristic feature:

A

Anatomy🧠 (10 decks)

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