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BIOL2220 > L10 Lipid metabolism > Flashcards

L10 Lipid metabolism Flashcards

1
Q

Substrate of the last beta-oxidation in a 5-C acyl-CoA, giving rise to one acetyl-CoA and what metabolite?

A

Propionyl- CoA

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2
Q

What is the product of glyoxylate cycle?

A

Succinate

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3
Q

Fatty acid oxidation generates what products?

A

Reduced electron carriers and acetyl-CoAs

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4
Q

Where does fatty acid activation take place?

A

Crystol

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5
Q

Does fatty acid activation takes up energy or generate energy?

A

Takes up energy (ATP→AMP)

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6
Q

Can fatty acyl-CoA pass through the inner membrane of mitochondira?

A

No

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7
Q

What is the carrier of fatty acyl chain to ener mitochondria?

A

Carnitine

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7
Q
A
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7
Q

What are the 4 major steps of beta-oxidation?

A

(1) Oxidation
(2) Hydration
(3) Oxidation
(4) Thiolysis

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7
Q

For each cycle of beta-oxidation, how many FADH2 and NADH are generated?

A

1 FADH2 and 1 NADH

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8
Q

How many ATP does the activation process take?

A

2 ATP
(technically 1, but that ATP is converted to AMP instead of ADP like usual)

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9
Q

What is the additional enzyme that is needed for oxidation of monounsaturated fatty acid?

A

derta 2, derta 3-enoyl-CoA isomerase

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10
Q

What are the additional enzymes that are needed for oxidation of polyunsaturated fatty acid?

A

derta 2, derta 3-enoyl-CoA isomerase and 2,4- dienoyl-CoA reductase

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11
Q

Under what condition are ketone bodies formed?

A

Starvation, after depletion of glucose supply

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12
Q

Does plant mitochondria contain beta-oxidation pathway enzymes?

A

No
Thus, as alternative, the glyoxylate cycle in plant seeds

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13
Q

Where does glyoxylate cycle take place?

A

In glyoxysomes, which is the organelle in developing seeds that reserve fats

14
Q

Acetyl-CoA produced by beta-oxidation enters the glyoxylate cycle to make which product?

A

succinate

15
Q

Glyoxylate cycle resembles which metabolic pathway?

A

Citric acid cycle

BIOL2220 (14 decks)

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