L10 Energy Generation 1 Flashcards

1
Q

__________, like bacteria, generate ATP using glycolysis

A

prokaryotes

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2
Q

Glycolysis is also called:

A

Anaerobic respiration (does not require oxygen)

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3
Q

(T/F) Glycolysis produces very small amounts of ATP compared to aerobic respiration

A

True

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4
Q

What is the most significant difference between prokaryotes and eukaryotes?

A

Eukaryotes use aerobic respiration to generate ATP ( utilize glycolysis as well, but as in initial step in aerobic respiration)

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5
Q

______ _____ is dependent on oxygen and produces C02 as a byproduct

A

Aerobic respiration

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6
Q

What is the opposite of aerobic respiration?

A

Photosynthesis in plants

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7
Q

Chlorophyll is a molecule that generates ____ and consumes ____

A

02; C02

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8
Q

Theory of losing oxygen and increasing C02 in atmosphere:

A

dysox theory

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9
Q

What are the two primary sources of fuel for aerobic respiration?

A
  1. Glycolysis of sugars

2. B-oxidation of fatty acids

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10
Q

Glycolysis produces:

A

2 pyruvic acids (pyruvate)
2 NADH
2 ATP

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11
Q

In B-oxidation, fatty acids are cut into _____ groups and are attached to _____, which directly produces an abundance of ______

A

Acetyl groups
coenzyme A
ACA- acetyl coenzyme A

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12
Q

What is the purpose of respiration?

A

To generate ATP

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13
Q

Aerobic respiration is a process of burning ____ with ____ to extract ATP from substrates

A

carbon

oxygen

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14
Q

Mitochondria have two fluid chambers within the organelle:

A
  1. Matrix

2. Inter-membrane space

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15
Q

The mitochondria has a _____ ______ between the matrix and inter-membrane space

A

concentration gradient

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16
Q

The outer membrane protects the inter-membrane space from influence of the ______

A

cytoplasm

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17
Q

The inner membrane encloses the matrix from the ___ ____

A

inter-membrane space

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18
Q

The inner membrane is deeply invaginated, and is called ______

A

cristae

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19
Q

What is the “battery” of the mitochondrion?

A

Inter-membrane space

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20
Q

The outer and inner membranes are specialized to keep __ in the space, while allowing ____ ___ of molecules through both membranes to maintain the factory

A

H+

selective transport

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21
Q

Channel proteins called _______ on the outer membrane selectively allow small molecules like ____ or ____ into the mitochondrion

A

porins

pyruvic acid or oxygen

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22
Q

2 examples of important molecules that pass through mitochondria with specialized transport mechanisms

A

acetyl coenzyme A (ACA)

glucose

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23
Q

The inner membrane includes the cristae and is embedded with:

A

Enzymes of the electron transport chain (Cytochrome P450 series enzymes, Coenzyme Q10)
ATP synthase
Substrate/ product transport proteins

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24
Q

Where does aerobic respiration take place?

A

Mitochondria of cells

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25
(T/F) Mitochondria is a closed system that facilitates generation of ATP
True
26
Mitochondria carries loops of ____ in the matrix that are constantly coding for the enzymes and proteins needed in these 4 processes:
DNA 1. B-Oxidation 2. Glycolysis 3. Krebs Cycle 4. Oxidative Phosphorylation
27
4 Steps of Aerobic Respiration: (all in mitochondria)
1. Pyruvate Decarboxylation- matrix 2. Krebs Cycle/ Citric Acid Cycle- matrix 3. Electron Transport Chain- cristae 4. ADP to ATP Phosphorylation- cristae
28
Where does (Step 1) Pyruvate Decarboxylation take place?
matrix of mitochondria
29
In pyruvate decarboxylation, pyruvic acid ( a 3-carbon molecule), has a ___ removed as ___
carbon; C02
30
What is the remainder of step 1 (pyruvate decarboxylation?
An acetyl group bonded to coenzyme A, making ACA, which enters the Krebs Cycle
31
Pyruvate Decarboxylation releases:
1 Co2 and 1 NADH
32
ACA is made in pyruvate decarboxylation and then enters:
The Krebs Cycle
33
Krebs cycle takes place in:
Matrix of mitochondria
34
Krebs Cycle breaks down the ____ pieces that enter from ACA by reacting them with ____ in a process called
2-carbon (acetyl) oxygen oxidation
35
The energy released from oxidation in Krebs Cycle is passed by energy carrier molecules to:
Electron Transport Chain (ETC)
36
The Krebs cycle oxidizes or burns ____ from ____ _____ or ______ via acetyl coenzyme A and releases CO2, which goes to LU
carbon pyruvic acid fatty acids
37
Step 3 (electron transport chain) ETC is lodged in the ____ membrane
cristae
38
The ___ ____ molecules produced from Krebs are utilized in ETC of enzymes
energy carrier
39
____ enzymes move electrons to power a build-up of energy in the mitochondria (battery)
ETC
40
What two ways is oxygen used in aerobic respiration?
1. Burnt with carbon | 2. Used as an electron acceptor, creating water
41
Step 4: Oxidative phosphorylation or __ ___ __
ATP synthase phosphorylation
42
In oxidative phosphorylation, the battery created by ETC is discharged across a membrane back into the mitochondrial matrix through the enzyme __ __
ATP synthase
43
The desire of the banked energy to _____ across the membrane's __ __ drives the enzyme to phosphorylate ADP to ATP
equilibriate | concentration gradient
44
What are the important molecular players in ATP energy generation?
1. Input molecules: Pyruvic acid, ACA, o2, ADP 2. Cofactors/ Enzymes 3. Vitamins 4. Output molecules: ATP, H+. C02 5. Mineral Ions
45
Step 1: Pyruvate Decarboxylations The first stage takes 3-carbon pyruvate from glycolysis, and convert pyruvic acid to ___ ___ ___ via the enzyme complex ___ ____
Acetyl coenzyme A (ACA) | Pyruvate Dehydrogenase
46
Step 1: Pyruvate Decarboxylations | Pyruvate Dehydrogenase Complex is:
A multi-unit enzyme
47
Step 1: Pyruvate Decarboxylations | How is ACA manufactured from pyruvate by Pyruvate Dehydrogenous Complex?
1. Pyruvate from glycolysis is degraded into an acetyl group using coenzyme lipoamide 2. Coenzyme A accepts the acetyl group, yielding ACA
48
fx of coenzyme lipoamide?
Degrades pyruvate into acetyl groups
49
Input and Output of Pyruvate Decarboxylation:
``` Input: Pyruvate Coenzyme A Coenzyme Lipoamide NAD+ O2 ``` ``` Output: NADH CO2 ACA Coenzyme Lipoamide ```
50
How is the 3-carbon molecule Pyruvate reduced to an acetyl group?
1 Carbon is released as CO2
51
NAD+ is used in creating ___, producing one NADH
CO2
52
Coenzyme lipoamide is recycled via:
FAD
53
Why is the Krebs Cycle often called the citric acid cycle?
Citric acid is the first molecular product when ACA is introduced to the cycle
54
The purpose of the Krebs Cycle is to _____ carbon from ___
oxidize (burn) | ACA
55
ACA is supplied to Krebs cycle from _____ ______ or ___ ___
Pyruvate Decarboxylation | B Oxidation
56
The products of NADH, FADH2, and succinate have excess ______ in their molecules that carry and extra ____ to feed the ETC
hydrogen | electron
57
_____ (4-carbon) is cycled into the 1st enzyme ( ___ ___) with ACA, creating citric acid- a 6- carbon molecule
Oxaloacetate | Citrate synthesase
58
What is the "work-horse" that the systems extracts energy from?
The 6 carbon backbone called citric acid
59
Krebs produces 3 ___, 1 ___ and 2 ____
3 NADH 1 FADH2 2 CO2
60
By breaking down carbon compounds and using oxygen, ___ ____ and ____ ____ sends the ETC 4 ____ and 1 _____
Pyruvate Decarboxylation Krebs Cycle 4 NADH 1 FADH
61
Waste products of ETC and Krebs cycle are:
3 CO2
62
NADH and FADH2 (energy intermediates) carry ____ to the ETC
hydrogen