L10 - Circadian Rhythms Flashcards
Describe biological rhythms
Cyclical changes in physiological systems which evolved due to the environment having cyclical changes (day/night and seasonal)
3 types
Circadian (24 hrs)
Ultradian (under 24 hrs)
Infradian (over 24 hrs)
The suprachiasmatic nuclei is located where and is what
In the hypothalamus
Pacemaker which controls the rate at which the body clock occurs
Why is the SCN reset?
Constantly reset so the body is in sync with the outside world
Describe photoentrainment
Natural light providing input to set the body clock to the correct time
Melanopsin acts as a brightness detector and sends messages about environmental light to the SCN
SCN uses info on natural light from photoentrainment to do what?
Coordinate activity of circadian rhythms
What is the sleep-wake cycle
Light and darkness determining when we need to sleep and when we wake up
Sleep-wake cycle is under what control
Homeostatic control
What happens when we’re awake for a long time?
Homeostasis tells us need for sleep is increasing due to amount of energy used when awake
Circadian rhythms are maintained between what hours
Between 24-25 even without natural light
SWC
Body temp is highest when
At 6pm
Body temp is lowest at
4:30am
Why does body temp rise just before we wake up?
So we feel alert
Small temp drop occurs
During 2-4pm
Melatonin is produced by
The pineal gland
What is melatonin’s function?
Inhibit neural mechanisms that promote sleepiness
More melatonin is produced when
During peak hours of darkness
Strongest sleep drives occur when?
2-4am
1-3pm
+ related to chronotherapeutics
Using circadian rhythms allow medication to be taken at right time to increase success
E.g. heart attack med isn’t released until 6am (most vulnerable time)
- related to individual differences
Differences in circadian rhythms
Some people prefer to sleep and wake early, some sleep and wake late
Study found it varies from 12-165 hours
- related to light
Doesn’t have to be natural light, can be artificial
Study using only artificial light changed from 22-28 hrs