L03 Flashcards
what is the function of the phospholipid bilayer
Allow for the passage of molecules in/out of cell.
what are the classes of proteins in the plasma membrane
transporters
linkers
receptors
enzymes
what are the types of transport
Passive transport
Active transport
what are the types of passive transport
facilitated diffusion (protein mediated)
simple diffusion
what is the difference between passive and active transport
passive transport goes with concentration gradient
active transport therefore requires energy (ATP)
carrier proteins are needed in both
what are the types of active transport
primary (pump mediated)
secondary (carrier mediated)
what are the types of primary active transport
Uniport (one molecule transported against concentration gradient)
cotransport (2 molecules transported in opposite directions against concentration gradient)
what are the types of secondary active transport
antiport (movement of 2 molecules in opposite directions 1 with concentration gradient)
symport (movement of 2 molecules in the same direction 1 of them against the concentration gradient)
what does the efflux of potassium do to the membrane potential.
makes it more negative
what does the efflux of chloride and influx of sodium do to the membrane potential
make it more positive
what is the resting membrane potential
The phase between action potentials
the cell is typically more negative inside than outside
True
what is the resting membrane potential for most mammalian cells
-50 mV
what are the steps involved in sodium-potassium pump
- cytoplasmic Na+ binds to the Na+/K+ pump
- the Na+/K+ pump is phosphorylated by ATP
- The pump changes its conformation, causing Na+ release
- extracellular K+ binds to the pump, leading to dephosphorylation
- the pump returns to its original conformation
- K+ is released from the pump
what is patch clamp electrophoresis
a way of investigating ion channels
