Kulick: Obesity

Question 1

Equation for BMI

Answer 1

weight/height^2 kg/m^2

Question 2

Normal BMI

Answer 2

18.5-24.9

Question 3

Overweight BMI

Answer 3

25-29.9

Question 4

Obese 1 BMI

Answer 4

30-34.9

Question 5

Pitfalls of BMI in describing obesity

Answer 5

underestimate/overestimate risk in populations, such as Asians, muscular individuals, short persons, older persons

Question 6

For an overweight or obese patient, a waist circumference of greater than (blank) for men, or greater than (blank) for women is associated with a greater risk of hypertension, type II diabetes, etc.

Answer 6

102cm; 88cm

Question 7

T/F: There are ethnic specific values for waist circumference

Answer 7

True

Question 8

Physicians only diagnose 1 in every (blank) obese patients

Answer 8

5

Question 9

Childhood obesity more common among these groups

Answer 9

American Indians
Non-hispanic blacks
Mexican Americans

Question 10

Having an obese parent increases the risk of obesity by (blank)-fold

Answer 10

2-3 fold

Question 11

Obesity persisting into adulthood dependent on these factors

Answer 11

Age (later onset–>more likely to persist)
Parental obesity
severity of obesity

Question 12

3 forms of obesity genetics

Answer 12

1. monogenic forms of obesity
2. syndromic forms of obesity
3. common obesity

Question 13

Several rare forms of obesity result from spontaneous mutations in single genes

Answer 13

Monogenic form

Question 14

Causes of monogenic form of obesity

Answer 14

leptin deficiency
human leptin receptor deficiency
melanocortin 4 receptor deficiency

Question 15

Perhaps the most common monogenic form of obesity in humans
Inherited in a co-dominant manner
Early onset hyperphagia, increased fat mass, increased lean mass, increased bone mineral density and bone mineral content, increased linear growth, and hyperinsulinemia

Answer 15

melanocortin 4 receptor deficiency (MC4R)

Question 16

Obesity occurring in the clinical context of a distinct set of associated clinical phenotypes.
Obesity is often accompanied by mental retardation, reproductive anomalies, or other health problems.

Answer 16

syndromic obesity

Question 17

T/F: Overweight and obesity account for a large percentage of cancer deaths in men (14%) and women (20%).

Answer 17

True

Question 18

Most important respiratory problem associated with overweight and obesity

Answer 18

obstructive sleep apnea

Question 19

About (blank) percent of people with Diabetes Mellitus is attributable to weight.

Answer 19

90%

Question 20

Is calorie consumption greater or less when liquids are consumed?

Answer 20

greater

Question 21

The most common syndromic form of obesity. Causes intrauterine and neonatal hypotonia, poor feeding during infancy, characteristic facial features, hypogonadism, short stature

Answer 21

Prader Willi Syndrome

Question 22

Bardet-Biedl syndrome

Answer 22

rare syndromic form of obesity

Question 23

What BMI is considered overweight for Asians? What BMI is considered obese?

Answer 23

23-24.9 overweight

>25 obese

Question 24

Criteria for metabolic syndrome

Answer 24

WC >102cm in men, >88cm in women
Fasting glucose > 100
Trigylcerides = 150
Reduced HDL 130/85