Kruse CIS thing Flashcards
How long do SSRI’s take to go into effect?
- 4-6 weeks
- benzos are much faster
can you give a benzo and an SSRI together?
-yeah for sure!
What is generalized anxiety disorder treated with?
-SSRI
What are benzos good for?
-short term symptom relief of crazy ppl
which way do we shift the dose response curve when we give a benzo?
- to the left
- that increases potency… less drug to get effects
Flumazenile, does it do anything when benzos arent there?
-no… remember that
what would we give someone who is going to have a bronchoscopy or something like that to induce anterograde amnesia and calm them down?
-Oxazepam
What drug class does chorpromazine fit under?
-antipsychotics
What is Zolpidem good for?
-sleep aid
What kind of antagonist is Flumazenil?
- a competitive one
- binds to benzo binding site on GABAa receptors and acts as a competitive antagonist
What drug do we use if someone is just having a lot of anxiety?
- Buspirone
- a lot of the other ones we might think about will have substance abuse risk
Which GABAa receptor agonists are appropriate choice to treat sleep problems
- Zolpidem (shortest half life so best choice)
- Eszopliclone
- Zalpelon
What enzyme does disulfiram inhibit?
- acetaldehyde dehydrogenase
- buildup of acetaldehyde and makes them feel like ASSSSSSSS
If someone is having a withdrawal syndrome because of the lack of CNS depressant, what drug should we give them?
-Lorazepam
If someone ingests methanol, what do we give them as an antidote?
- Ethanol
- higher affinity for ADH
- fomepizole also works because it inhibits ADH directly
