Krebs Cycle

Question 1

What stimulates fatty acid production?

Answer 1

Lipids

Question 2

What intermediate in the Kreb’s cycle is necessary to make hemoglobin?

Answer 2

Succinyl coA

Question 3

What 2 amino acids are easiest to make?

Answer 3

Aspartate and glutamate

Question 4

Starting molecule of Kreb’s?

Answer 4

Acetyl coA

Question 5

Glucose is converted to pyruvate in what cycle?

Answer 5

Glycolysis

Question 6

What coenzymes are needed for pyruvate dehydrogenase?

Answer 6

B1, B2, B3, B5, lipolic acid

Question 7

First compound of Kreb’s cycle and enzyme?

Answer 7

Citrate and aconitase

Question 8

What is purpose of aconitase in enzyme in step 2 of Kreb’s?

Answer 8

No net synthesis of glucose.

Question 9

What two minerals support the function of aconitase?

Answer 9

Iron and sulfur proteins

Question 10

What is the allosteric enzyme in TCA cycle?

Answer 10

Isocitrate dehydrogenase

Question 11

What two compounds can inhibit isocitrate dehydrogenase?

Answer 11

NADH and ATP

Question 12

What is the name of the enzyme that uses all the same enzymes as pyruvate dehydrogenase?

Answer 12

Alpha ketoglutarate dehydrogenase

Question 13

What compound can be made from succinyl coA?

Answer 13

Heme

Question 14

What enzyme converts pyruvate to OAA and what are the enzymes?

Answer 14

Pyruvate carboxylase.
Needs biotin and ATP.

Question 15

What is the location in the mitochondria in all other Kreb’s cycle enzymes?

Answer 15

In matrix

Question 16

What type of diet increases OAA concentration?

Answer 16

High carb

Question 17

What can muscles not contract without?

Answer 17

Calcium

Question 18

What slows down rate of Kreb’s in a high alcohol diet?

Answer 18

NADH production

Question 19

What shuts off PFK?

Answer 19

High levels of citric acid on glycolysis

Question 20

Lack of exercise does what to Krebs cycle?

Answer 20

Slows it down

Question 21

What pathway is turned on by high levels of citrate in cytoplasm?

Answer 21

Fatty acid synthesis

Question 22

Name amino acids that enter as pyruvate

Answer 22

Alanine, glycine, cystine, serine, threonine, tryptophan

Question 23

What amino acids enter as alpha ketoglutarate?

Answer 23

HAPGG
Histidine
Arginine
Proline
Glutamate
Glutamine

Question 24

What amino acids enter as succinyl coA?

Answer 24

VIM
Valine
Isoleucine
Methionine

Question 25

What amino acids enter as fumarate?

Answer 25

PAT is fuming Phenylalanine Asparate Tyrosine

Question 26

What amino acids enter as OAA?

Answer 26

Aspartate and asparagine

Question 27

What amino acids are always together?

Answer 27

Phenylalanine and tyrosine

Question 28

List the amino acids that are both ketogenic and glutogenic?

Answer 28

PITT Phe Tyr Tryptophan Isoleucine

Question 29

What compounds that enter as Acetyl coA are only ketogenic?

Answer 29

Lysine and leucine. Fatty acids.

Question 30

Ketogenic compounds always enter as what?

Answer 30

Acetyl coA