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Nutrition And Metabolism > Krebs Cycle > Flashcards

Krebs Cycle Flashcards

1
Q

What stimulates fatty acid production?

A

Lipids

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2
Q

What intermediate in the Kreb’s cycle is necessary to make hemoglobin?

A

Succinyl coA

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3
Q

What 2 amino acids are easiest to make?

A

Aspartate and glutamate

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4
Q

Starting molecule of Kreb’s?

A

Acetyl coA

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5
Q

Glucose is converted to pyruvate in what cycle?

A

Glycolysis

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6
Q

What coenzymes are needed for pyruvate dehydrogenase?

A

B1, B2, B3, B5, lipolic acid

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7
Q

First compound of Kreb’s cycle and enzyme?

A

Citrate and aconitase

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8
Q

What is purpose of aconitase in enzyme in step 2 of Kreb’s?

A

No net synthesis of glucose.

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9
Q

What two minerals support the function of aconitase?

A

Iron and sulfur proteins

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10
Q

What is the allosteric enzyme in TCA cycle?

A

Isocitrate dehydrogenase

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11
Q

What two compounds can inhibit isocitrate dehydrogenase?

A

NADH and ATP

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12
Q

What is the name of the enzyme that uses all the same enzymes as pyruvate dehydrogenase?

A

Alpha ketoglutarate dehydrogenase

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13
Q

What compound can be made from succinyl coA?

A

Heme

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14
Q

What enzyme converts pyruvate to OAA and what are the enzymes?

A

Pyruvate carboxylase.
Needs biotin and ATP.

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15
Q

What is the location in the mitochondria in all other Kreb’s cycle enzymes?

A

In matrix

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16
Q

What type of diet increases OAA concentration?

A

High carb

17
Q

What can muscles not contract without?

A

Calcium

18
Q

What slows down rate of Kreb’s in a high alcohol diet?

A

NADH production

19
Q

What shuts off PFK?

A

High levels of citric acid on glycolysis

20
Q

Lack of exercise does what to Krebs cycle?

A

Slows it down

21
Q

What pathway is turned on by high levels of citrate in cytoplasm?

A

Fatty acid synthesis

22
Q

Name amino acids that enter as pyruvate

A

Alanine, glycine, cystine, serine, threonine, tryptophan

23
Q

What amino acids enter as alpha ketoglutarate?

A

HAPGG
Histidine
Arginine
Proline
Glutamate
Glutamine

24
Q

What amino acids enter as succinyl coA?

A

VIM
Valine
Isoleucine
Methionine

25
Q

What amino acids enter as fumarate?

A

PAT is fuming
Phenylalanine
Asparate
Tyrosine

26
Q

What amino acids enter as OAA?

A

Aspartate and asparagine

27
Q

What amino acids are always together?

A

Phenylalanine and tyrosine

28
Q

List the amino acids that are both ketogenic and glutogenic?

A

PITT
Phe
Tyr
Tryptophan
Isoleucine

29
Q

What compounds that enter as Acetyl coA are only ketogenic?

A

Lysine and leucine. Fatty acids.

30
Q

Ketogenic compounds always enter as what?

A

Acetyl coA

Nutrition And Metabolism (4 decks)

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