Bioenergetics

Question 1

Which complex’s enzyme is NADH-Q reductase?

Answer 1

Complex I

Question 2

Which complex does FMN to FeS to ubiquinone?

Answer 2

Complex I

Question 3

Which complex has no cytochromes?

Answer 3

Complex I

Question 4

In which complex is NADH oxidized?

Answer 4

Complex I

Question 5

In which complex is the enzyme glycerol 3 phosphate-Q reductase?

Answer 5

Complex G

Question 6

Which complex is located in skeletal muscle?

Answer 6

Complex G

Question 7

Which complex does FAD to FADH2 to FeS to ubiquinone?

Answer 7

Complex G

Question 8

In what complex is the enzyme succinate dehydrogenase?

Answer 8

Complex II

Question 9

Complex II does what?

Answer 9

FAD to FADH2 to FeS to ubiquinone

Question 10

What complex’s enzyme is fatty acetyl co A dehydrogenase?

Answer 10

Complex F

Question 11

What complex’s enzyme is ubiquinone-cytochrome 6 reductase?

Answer 11

Complex III

Question 12

What does complex III do?

Answer 12

Cytochrome b to FeS center to cytochrome CI to cytochrome C

Question 13

Which complex has enzyme cytochrome C oxidase?

Answer 13

Complex IV

Question 14

What does complex IV do?

Answer 14

Pump out 4 PROTEINS!

Question 15

What is unique about cytochrome C oxidase?

Answer 15

It is copper dependent

Question 16

Ubiquinone is also known as?

Answer 16

Coenzyme Q10

Question 17

What food has 9 kcals per gram?

Answer 17

Fats

Question 18

What has 7 kcals per gram?

Answer 18

Alcohol

Question 19

What has 4 kcals per gram?

Answer 19

Carbs

Question 20

What pathway oxidizes fuels such as carbs and fats and reduces nucleotides?

Answer 20

Krebs cycle

Question 21

Where is Krebs cycle located?

Answer 21

Mitochondrial matrix

Question 22

What is energy produced by electron transport used for?

Answer 22

Pumping protons out

Question 23

ATP produced by what enzyme?

Answer 23

ATP synthase

Question 24

What reduced nucleotide enters at complex I?

Answer 24

NADH

Question 25

What shuttle does NADH use to enter mitochondria from cytoplasm?

Answer 25

DHAP

Question 26

Complex G functions like?

Answer 26

Complex II

Question 27

What reduced nucleotide enters at complex II?

Answer 27

FAD

Question 28

What is the shuttle for NADH named in heart and liver?

Answer 28

Malate-aspartate shuttle

Question 29

What enzyme is needed for malate-aspartatate shuttle?

Answer 29

SGOT

Question 30

Examples of high energy compounds?

Answer 30

Phosphocreatine Phosphoenypyruate Acetyl co A 1,3 biphosphoglycerate Pyrophosphate

Question 31

How are large proteins transported in and out of mitochondria?

Answer 31

Outer membrane of mitochondria using TOMs

Question 32

What is the location of oxidative phosphorylation (the electron transport chain)?

Answer 32

Inner mitochondrial membrane

Question 33

Where is ubiquinone located?

Answer 33

Inner mitochondrial membrane

Question 34

What is location of cytochrome C?

Answer 34

Innermembranous side of inner mitochondrial membrane

Question 35

What complexes pump protons out of matrix and into intramemrbaous space?

Answer 35

I, III, IV

Question 36

Which complex contains the allosteric enzyme?

Answer 36

IV

Question 37

What can inhibit ADP-ATP translocase in mitochondria?

Answer 37

Mold and plant toxins

Question 38

List the inhibitors of complex I?

Answer 38

Rotenone

Question 39

Inhibitor of complex III?

Answer 39

Antimycin A

Question 40

Inhibitor of complex IV?

Answer 40

CO and cyanide