Krebs cycle

Question 1

Step 1: ?

enzyme ___ removes Acetyl Group and tacks it on to ____ to form ___

Answer 1

Transfer of Acetyl Group;

enzyme CITRIC SYNTHASE removes Acetyl Group and tacks it on to OXALOACETATE to form CITRATE

Question 2

aerobic respiration occurs in

Answer 2

mitochondria

Question 3

in the presence of NAD+ pyruvate will undergo ___ , ____and ____ to form ____

Answer 3

undergo; Decarboxylation, Oxidation, Attachment to Coenzyme A

to form; Acetyl- CoA

Question 4

Citric acid cycle a.k.a

Answer 4

Krebs cycle or Tricarboxylic Acid Cycle

Question 5

Step 2: ?

With the help of ____, a ____ molecule is removed and another one is ____ to generate a structural isomer of citrate called _____

Answer 5

Isomerization;

With the help of ACONITASE, a WATER molecule is removed, and another one is ADDED to generate a structural isomer of citrate called ISOCITRATE

Question 6

Step 3: ?

Catalyzed by ____. isocitrate is oxidized by ____ and then decarboxylates to form ________

Answer 6

Oxidation/ decarboxylation

Catalyzed by ISOCITRATE DEHYDROGENASE. isocitrate is oxidized by NAD+ and then decarboxylates to form ALPHA - KETOGLUTARATE

Question 7

Step 4;

Another ___ is lost, and further oxidation by _____ takes place, with the help of ____. The resulting molecule will join with Coenzyme a. Once again, to form ____

Answer 7

Rejoining with CoA

Another CO2 is lost, and further oxidation by NAD+ takes place, with the help of KETOGLUTARATE DEHYDROGENASE. The resulting molecule will join with Coenzyme a Once again, to form SUCCINYL-CoA

Question 8

Step 5; ?

CoA is then displaced by a phosphate group to form _____. This is catalyzed by _____. This will make 1 molecule of _____ which can be used to make 1 ATP

Answer 8

Foramtion of GTP

CoA is then displaced by a phosphate group to form SUCCINATE. This is catalyzed by SUCCINYL-CoA SYNTHETASE. This will make 1 molecule of GUANOSINE TRUPHOSPHATE or GTP which can be used to make 1 ATP

Question 9

Step 6: ?

With the help of ___, succinate is oxidized by a different molecule, ____, which will result in ______ and ______

Answer 9

Oxidation by FAD

With the help of SUCCINATE DEHYDROGINASE, succinate is oxidized by a different molecule, FAD, which will result in FUMARATE and FADH2

Question 10

Step 7: ?

_____ will catalyze Hydration. which will result in ______

Answer 10

Hydration

FUMARASE will catalyze HYDRATION. which will result in MALATE

Question 11

Step 8: ?

One more oxidation by ____ takes place with the help of ________ which give ______ which will restart the cycle

Answer 11

Final Oxidation

One more oxidation by NAD+ takes place with the help of MALATE DEHYDROGENASE which give OXALOACETATE which will restart the cycle reacting with a new Acetyl-CoA

Question 12

Overall, the citric acid cycle will produce:

Answer 12

3 NADHs, 1 FADH2, and 1 ATP

but since 2 pyruvate will be produced in glycolysis, therefore 2 Acetyl Coa KAYA DODOBLEHIN

6 NADHs, 1 FADH2, and 1 ATP
(per glucose)