Knowledge Burst Unit 3

Question 1

The following RBC indices are obtained on a patient when calculated using results from manual methods:
MCV: 73 fL
MCH: 24 pg
MCHC: 33.4 g/dL
When the stained blood film is evaluated, the RBC are normocytic and normochromic. What conclusion can be made from this information?

Answer 1

the red count is too high (MCV and MCH out of range)

Question 2

how do sickle cell or spherocytes interfere with the ESR?

Answer 2

prevent rouleaux formation, so falsely decrease

Question 3

What is a good use of the ESR

Answer 3

monitor patients with RA

Question 4

the red blood count is 3.22 x 10^12 /L and the HCT is 30%. Calculate the MCV

Answer 4

93 fL
MCV = 30/3.22x10 =93

Question 5

which of the following red cell indicies support microcytic hypochromic red cell morphology

Answer 5

mcv - 68
mch- 22
mchc- 28

Question 6

a hemoglobin of 19 g/dL is normal for which of the following patients?

Answer 6

a newborn

Question 7

which of the following correctly describes the structure of normal hemoglobin A (Hb A)

Answer 7

2 alpha and 2 beta chains, each containing one home group

Question 8

all of the following hemoglobins are found in a normal human adult except:

Answer 8

Hemoglobin Gower-2

Question 9

why is it important that synthesis of globin chains and heme be balanced in the RBCs

Answer 9

an excess of one of the components of hemoglobin decreases RBC survival

Question 10

why does HbF have a higher oxygen affinity than adult hemoglobin

Answer 10

it is necessary to extract oxygen from the maternal blood supply