Klinefelter's syndrome

Question 1

Define Klinefelter’s syndrome

Answer 1

Males have an additional X chromosome (Karyotype 47, XXY)

Question 2

What is the karyotype in Klinefelter’s syndrome

Answer 2

Karyotype 47, XXY

Additional “X” chromosome

Question 3

Name some of the features of Klinefelter’s syndrome

Answer 3

Taller than average height

Wider hips

Lack of secondary sexual characteristics e.g., facial, chest hair, upper body muscular build

Small testicles

Reduced libido

Infertility

Gynaecomastia

Question 4

What is the normal male karyotype

Answer 4

Karyotype 46, XY