KIN 4500 Flashcards
Physical/Chemical barriers/immune cells
Innate Immunity
Humoral/cell mediated
Adaptive Immunity
White blood cells are defined by
Leukocytes
Provides a mechanism for communication between immune cells
Cytokines
Plasma proteins that kill extracellular pathogens
Complement
Glycoproteins released from the liver that are involved in inflammation
Acute Phase Proteins
What cytokine/myokine is produced in large amounts during muscle contractions?
Interleukin-6
Responsible for mediating inflammation and allergic response
Basophils
Role is to ingest and destroy invaders; phagocytic
Neutrophils
Age-related changes in the immune system.
Examples: decreased ability to fight cancer or infections
Immnuosenescence
T-Cells
“Able to differentiate into other types of T-cells with a functional purpose in the immune system”
Naiive
T-Cells
“Hold on to some “memory” of antigenic encounters to fight off a similar invader in the future”
Memory
Increase blood flow
Dilation
Increased permeability
Extravasation
Leukocytes to injury
Chemoattraction
Fever; leukocytosis
Systemic response
Exogenous Antioxidant
Ascorbic Acid (Vitamin C)
Alpha-tocopherol (Vitamin E)
Resveratrol
Zinc
Reactive Oxygen and Nitrogen Species
RONS
Exercise increases in generations of RONS
True
Large class of naturally occurring compounds that include flavonoids . flavonols, flavonones, and anthocyanidins
Polyphenols
Antioxidant enzyme systems are increased in response to exhaustive exercise in younger but not older adults
True
Avoiding disease and disability
Biology
Maintaining higher cognitive functioning
Psychology
Continued engagement with life
Social
Short Physical performance battery assesses
- Balance
- Lower body strength/endurance
- Walking speed
Memory, attention, and executive functions decrease with advanced age
Cognitive decline
1-2% of muscle mass loss per year after age 50
Sarcopenia
Loss of muscle strength as a person ages
Dynapenia
Behavioural risk declines
- Over nutrition
- Poor Sleep
- Sedentary Lifestyle
Normal human aging includes
- Structural and functional decline
- Declining physical activity
- Increased risk of chronic disease
What aging process do we have the most control over
Secondary aging process (chronic disease, lifestyle behaviours, and genetic factors)
Pre-screening tool used for assessing older adults
- GAQ
- PAR-Q+
- AAPQ
Asymptomatic and have no more than one major risk factor
Low CHD Risk (Coronary Heart Disease)
Individuals having 2 or more major risk factors
Moderate CHD Risk
Have one or more signs and symptoms of cardiovascular, pulmonary or metabolic disease or individuals with known cardiovascular, pulmonary or metabolic disease
High CHD Risk
Short term change in behaviour
Lapse
Type of goal that has has least personal behavioural control over meeting it
Outcome goal