Kidneys Flashcards
kidney
main function is osmoregulation
osmoregulation
Balances salt and water in the blood
Maintains levels of other Ions
Eg. potassium (K+), bicarbonate (HCO-), calcium (Ca+)
Vitamin D
acts like a hormone because it promotes the absorption of calcium from our digestive tract
erythropoietin (EPO)
secreted by kidneys when O2 is needed
Stimulates production of RBC
Metabolic wastes
Normal waste products made by functioning cells
Enter the blood in the capillaries in each cell
Carried to the kidneys where they are removed from the body
4 Functions of the kidneys
1) Excretion of metabolic wastes
2) Osmoregulation
3) Regulation of Acid-Base Balance
4) Secretion of hormones
Excretion of metabolic wastes
kidneys get rid of mainly nitrogenous waste like urea, ammonia, creatine, and uric acid
Creatine phosphate
stores high-energy phosphate in muscles and breaks down into creatinine for removal
Nucleotide breakdown produces uric acid, which is insoluble
Excess uric acid can form crystals in joints, causing gout.
Osmoregulation
need to reabsorb water
keeps balance of water and salt into the body
How is blood volume related to salts in the body
salts have ability to cause osmosis in the blood
Increase in salt = increase in blood volume = increase in blood pressure
kidneys also help to balance blood pressure
Regulation of Acid-Base Balance
respiratory system and kidneys regulate acid base balance in body
how are kidneys and blood pH related
Kidneys monitor and keep the blood pH around 7
excretes hydrogen and reabsorbs bicarbonate ions to monitor pH
urine usually has pH of 6 or lower because diets have acidic foods
Secretion of hormones
kidneys assist the endocrine system
renal capsule
tough tissue covering kidneys
hilium
lower side of concave side of each kidney
This is where renal artery enters and renal vein exits
Adrenal Glands
renin
regulates blood pressure and helps keep water and sodium
Renin is an enzyme that leads to the secretion of the hormone aldosterone
Adrenal cortex
Outer portion of the adrenal glands
Nephron
Area of the kidneys that remove waste
Each nephron has its own blood supply (from renal vein and artery)
Bowman capsule (glomerular capsule)
Cup like structure
Allows for passage of small molecules
Eg. amino acids, water, glucose, salt, urea
where are glomerulus found
Found inside nephrons
Knot of capillaries
Made of capillaries intertwined with tubles
glomerulus
Act as a sieve to filter out waste products which keep normal protein and cells in the bloodstream
2 portions of blood in glomerulus
1) Filterable blood components (water, nitrogenous wastes, nutrients, salts)
2) Non- filterable blood components (blood cells, platelets, plasma proteins)
Renal artery
Branches off from aorta
Brings blood full of waste into kidneys
Afferent
going towards
Efferent
going away
Pathway of blood in kidneys
Renal artery → arteries → afferent arterioles → glomerulus → efferent arteriole capillaries → venule → renal vein
why does afferent arteriole have a larger diameter
increase blood pressure in the bowman’s capsule
Renal vein
Removes filtered blood from kidneys and take it to the inferior vena cava
Venules join to form small veins, which form the renal vein
3 Regions of the kidney
1) Renal cortex
2) Renal medulla
3) Renal pelvis
Renal cortex
outer region
mainly made up of nephrons
Bowman capsule is found here
Renal medulla
middle region
collection area
empties in the renal pelvis
Renal pelvis
inner region
receives urine from the nephrons
connects to the ureter
3 Steps to waste removal in the kidneys
1) Glomerular filtrations
2) Tubular reabsorption
3) Tubular secretion
Glomerular filtrations
occur in glomerulus
fluids forced out of capillary walls because of pressure of blood entering kidneys
filtrate
made of water, glucose, amino acids, salt, and urea
our bodies want to save nutrients (not pee them out)
Tubular reabsorption
the nutrients that go back into the blood (sugar, nutrients, salts)
passively and actively reabsorbed from nephron into blood of capillaries
how does water and nutrients move during tubular reabsorption
water moves by osmosis and nutrients move by diffusion
Tubular secretion
2nd filtering process
kidneys remove more things out of blood (filter it again) and adds them to what is left
once secretion is finish the filtrate is called urine