Kidneys Flashcards

1
Q

What are the functions of kindeys?

A

To regulate water content in the blood and remove toxic waste from the metabolism

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2
Q

What blood vessels are the kidneys placed on?

A

On the right, the renal artery, on the left the renal vein

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3
Q

What carries urine from the kidneys to the bladder?

A

The ureter

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4
Q

What is urea?

A

The nitrogenous waste product from breaking down protein which is excreted in urine

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5
Q

What does the renal artery branch off?

A

The aorta

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6
Q

What is urine expelled through?

A

The urethra

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7
Q

Where does purified blood return to the cycle?

A

Through the renal vein

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8
Q

What is the kidney packed with?

A

Nephrons

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9
Q

Where are the nephrons?

A

They start in the cortex of the kidney and loop down into the medulla and back to the cortex

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10
Q

What does the nephron do?

A

It regulates the level of water and salts and removes urea from the blood

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11
Q

Appreciate this :)

A
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12
Q

What is the bowman’s capsule?

A

A part of the nephron - a cup like structure which surrounds the capillary knot

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13
Q

How is high pressure in the capillary knot created?

A

By the diameter of the capillary leaving the knot being narrower than the capillary entering

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14
Q

What does pressure in the capillary knot result in?

A

Ultrafiltration, where salts, water, glucose and other small molecules pass out of the capillary knot into the bowman’s capsule

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15
Q

Which things are too big for ultrafiltration?

A

Proteins and blood cells

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16
Q

What is the rest of the tubule responsible for?

A

The selective reapsorbtion of glucose, some salts, and lots of water.

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17
Q

What is the collecting duct responsible for?

A

The selective reabsorption of water and sending urine to the ureter

18
Q

What does ADH stand for and what is it?

A

Anti diuretic hormone and it’s anti weeing hormone

19
Q

What is water in the blood controlled by?

20
Q

What is the release of ADH from a gland in the brain controlled by?

A

Blood plasma concentration

21
Q

What can the concentration of blood be altered by?

A
  • Excess drinking
  • Excess sweating
    • Consumption of salty foods
22
Q

Which gland releases ADH?

A

The pituitary gland

23
Q

What is the release of ADH?

A

A negative feedback mechanism

24
Q

How is diabetes diagnosed?

A

If there is glucose in the urine

25
What does protein in the urine suggest?
Damage in the kidney
26
What do people with kidney damage need to do to clear their blood?
Dialysis
27
What are the positives of dialysis
* It can keep a patient alive whilst they are waiting for a suitable donor to be found * It does not involve major surgery
28
What are the disadvantages of dialysis?
* Patients need to follow a carefully controlled diet. * Patients need to spend many hours every week attached to a dialysis machine. * Dialysis machines are very expensive. * Dialysis will only be successful for a certain amount of time.
29
Where are donor kidneys connected?
Near the bladder
30
What is the most major problem with a transplant?
Rejection
31
What drugs do people with transplants need to take?
Immunosuppresant
32
Which people are most likely to have similar tissue types?
Family
33
What are the advantages of kidney transplants?
* Once the transplant has occurred the patient no longer has diet restrictions. * Long periods of time on dialysis are no longer necessary. * Although not a life-long cure, a kidney transplant will generally allow the patient to live a fuller life for longer than a patient on dialysis.
34
What are the disadvantages of kidney transplants?
* It is difficult to find a donor organ with a matching tissue type. * The risk of organ rejection. * Having to take drugs which suppress the immune system, leaving the patient susceptible to contracting other diseases. * Regular doctors' appointments to detect signs of organ rejection. * Major surgery is required.
35
What happens during dialysis?
Blood is removed from the patient and flows into the dialyzer where it is kept separated from dialysis fluid by a **partially permeable** membrane.
36
What does the dialysis fluid contain?
The same concentration of glucose and salts as normal blood plasma so there is no net movement of glucose out of the blood by diffusion
37
What happens to excess salt in the bloodstream?
It diffuses into the dialysis fluid
38
What happens to urea in the bloodstream during dialysis?
Because dialysis fluid contains no urea, almost all the urea diffuses into the dialysis fluid
39
How are concentration gradients maintained during dialysis?
Using a counter current system - bloodstream and dialysis flowing in opposite directions
40
What happens after dialysis?
The clean blood is returned to the patient and the waste dialysis fluid is disposed of