Kidney Transplant Treatment & Complications

Question 1

what is the induction treatment used for kidney transplant

Answer 1

Basiliximab/Dacluzimab

and IV prednisolone during operation

Question 2

what is the maintenance treatment used for kidney transplant

Answer 2

usually prednisolone, tacrolimus and mycophenolate mofetil

Question 3

what drugs are used to treat antibody mediated rejection

Answer 3

anti-thymocyte globulin, IV immunoglobin, plasma exchange, rituximab

Question 4

what drugs are used to treat cellular mediated rejection

Answer 4

pulsed IV methylprednisolone and if not working then anti-thymocyte globulin

Question 5

what is the most common infection complication of the transplant treatment

Answer 5

PJP infection, due to suppression of immune system

UTI and LRTI also common

Question 6

what is CMV disease complication in kidney transplant associated with

Answer 6

first 3 months of transplant, early graft loss, if recipient not immune but donor has had previous CMV infection

Question 7

what complication can be caused by over immunosuppression

Answer 7

BK nephropathy, treat by reducing immunosuppression

Question 8

what can BK nephropathy mimic

Answer 8

kidney rejection

Question 9

what are some of the causes of graft loss in kidney transplants

Answer 9

acute/chronic rejection, recurrent disease, viral nephropathy