kidney disorders Flashcards
kidneys receive ___% of total cardiac output
25
contains nephrons
cortex
inner portion containing loop of henle, vasa recta, collecting ducts
medulla
responsible for the formation of filtrate that becomes urine
nephrons
once less than ___% of nephrons are functions, a pt is in end stage renal failure
15-20
normal GFR
90-125
these should never leave the body in urine
protein, glucose
hyperkalemia can lead to
cardiac arrhythmias
what can lower GFR
HTN, hyperlipidemia
T/F: the kidneys can endogenously produce bicarbonate for acid-base control
T
what do the kidneys make that are responsible for signaling bone marrow to produce RBCs?
erythropoietin (EPO)
what vitamin do the kidneys produce?
vitamin D (active form)
s/s:
- dyspnea
- tachycardia
- JVD
- peripheral edema
- pulmonary edema
- wt gain
hypervolemia
s/s:
- decreased UOP
- wt loss
- decreased skin turgor
- dry mucous membranes
- hypertension
- tachycardia
hypovolemia
nitrogen in the blood
azotemia
WASTE in the blood
uremia
chronic kidney disease is classified as a GFR of ___ lasting for ____months or longer
<60, 3
what will pt labs look like for chronic kidney disease?
decreased GFR, increased BUN & Cr, metabolic acidosis
what drug resolves metabolic acidosis
sodium bicarbonate (exogenous)
this signifies end stage kidney disease
uremia
s/s chronic kidney disease
CAD, anorexia, hyperparathyroidism, anemia, osteomalacia, uremia*
reversible causes CKD include
hypovolemia (diuretic use, vomiting, bleeding from sepsis, chronic NSAID use, contrast), urinary obstruction, BP
what drugs are used for BP control?
ACE inhibitors, ARBS
this nutrient should be restricted in kidney diseases
protein
treatment for acute anemia
transfusions
treatment for chronic anemia
exogenous EPO
drug used for dyslipidemia treatment
statins
treatment of fluid volume overload
loop diuretic (furosemide/lasix)
treatment hyperkalemia
k-exelate, low K diet