Keywords Flashcards
Topic : Causes of disease
Pathogen
A micro-organism that causes disease
Topic : Enzymes and Digestive system
Digestion
Physical and chemical breakdown of food
Topic : Enzymes and Digestive system
Hydrolysis
Splitting up of molecules by adding water to them.
Enzymes do this to help break down molecules.
Topic : Enzymes and Digestive system
Monomer
One of many small molecules that combine to form a
larger one
Topic : Enzymes and Digestive system
Polymer
Larger molecule made up of repeating smaller
molecules
Topic : Enzymes and Digestive system
Condensation Reaction
When 2 monosaccharides combine, water is removed
Topic : Enzymes and Digestive system
Glycosidic Bond
The bond in a disaccharide
Topic : Enzymes and Digestive system
Peptide Bond
The bond between 2 amino acids in a protein, formed
by a condensation reaction
Topic : Enzymes and Digestive system
Polypeptide
A long chain of amino acids
Topic : Enzymes and Digestive system
Hydrogen Bonds
Weak bonds between oxygen and hydrogen holding the
secondary structure of a protein in a coil
Topic : Enzymes and Digestive system
Activation Energy
The minimum amount of energy needed to bring about
a reaction
Topic : Enzymes and Digestive system
Active site
The region on an enzyme where the substrate fits
Topic : Enzymes and Digestive system
Substrate
The molecule on which the enzyme acts
Topic : Enzymes and Digestive system
Enzyme-Substrate Complex
Formed when an enzyme and a substrate fit together
and form temporary bonds
Topic : Enzymes and Digestive system
Denaturation
Permanent changes in the structure of a protein;
enzyme’s active site changes shape so the substrate no
longer fits
Topic : Enzymes and Digestive system
Competitive Inhibitor
Molecule that binds to the active site of an enzyme
Topic : Enzymes and Digestive system
Non-competitive inhibitor
Bind to the enzyme at a position other than the active
site
Topic : Cells and movement in and out of them
Resolution
The minimum distance apart 2 objects are, so that they
look like separate objects under the microscope
Topic : Cells and movement in and out of them
Cell Fractionation
The process by which cells are broken up and the
organelles separated out
Topic : Cells and movement in and out of them
Prokaryotic Cells
Cells that lack a nucleus and any membrane-bound
organelles
Topic : Cells and movement in and out of them
Eukaryotic Cells
Cells that have a nucleus, chromosomes and other
membrane-bound organelles
Topic : Cells and movement in and out of them
Saturated Lipids
Fatty acids with only C-C single bonds
Topic : Cells and movement in and out of them
Unsaturated Lipids
Fatty acids with one or more C=C double bonds
Topic : Cells and movement in and out of them
Hydrophilic
Attracted to water
Topic : Cells and movement in and out of them
Hydrophobic
Attracted to fat
Topic : Cells and movement in and out of them
Extrinsic Proteins
Proteins on the surface of the bilayer
Topic : Cells and movement in and out of them
Intrinsic Proteins
Proteins spanning the bilayer
Topic : Cells and movement in and out of them
Diffusion
The net movement of molecules or ions from a region
of high concentration to a region of low concentration
Topic : Cells and movement in and out of them
Osmosis
The passage of water from a region of high water
potential to a region of low water potential, across a
partially permeable membrane
Topic : Cells and movement in and out of them
Active Transport
The movement of molecules or ions into or out of a cell
from a region of lower concentration to a region of
higher concentration using energy and carrier
molecules
Topic : Lungs and Lung Disease
Pulmonary
Ventilation
Tidal Volume x Ventilation Rate
Topic : Lungs and Lung Disease
Short Diffusion Pathway
Thin alveoli walls allow materials to cross quickly as the
path is short
Topic : Lungs and Lung Disease
Diffusion Gradient
Movement of air and blood help to maintain diffusion
gradients – keep Oxygen moving in and CO2 out
Topic : Lungs and Lung Disease
Pulmonary Fibrosis
Thickening of lung epithelia due to scarring
Topic : Lungs and Lung Disease
Asthma
An allergic reaction where histamine is released and the
airway linings become inflamed
Topic : Lungs and Lung Disease
Emphysema
Destruction of the elastic tissue in the lungs due to
smoking
Topic : The Heart and Heart Disease
Atrial Systole
Contraction of the atria
Topic : The Heart and Heart Disease
Ventricular Systole
Contraction of the ventricles
Topic : The Heart and Heart Disease
Diastole
Relaxation of the heart
Topic : The Heart and Heart Disease
Cardiac Output
The volume of blood pumped by one ventricle of the
heart in one minute
Topic : The Heart and Heart Disease
Myogenic
Contraction of the heart is initiated from within the
muscle itself
Topic : The Heart and Heart Disease
Sino-atrial node
SAN, sends out the initial wave of electrical activity to
make the atria contract
Topic : The Heart and Heart Disease
Atrio-ventricular node
AVN, sends a wave of electrical activity down the
bundle of His, making the ventricles contract from the
base upwards
Topic : The Heart and Heart Disease
Atheroma
A fatty deposit in the wall of an artery
Topic : The Heart and Heart Disease
Aneurysm
Weakened artery walls swell and may burst
Topic : The Heart and Heart Disease
Thrombosis
When an atheroma breaks and a blood clot forms
Topic : The Heart and Heart Disease
Myocardial Infarction
A heart attack
Topic : The Heart and Heart Disease
Low-density lipoproteins
Transport cholesterol to tissues that may get deposited
Topic : The Heart and Heart Disease
High-density lipoproteins
Remove cholesterol from tissues
Topic : Immunity
Non-Specific Defences
Mechanisms that don’t distinguish between one type of
pathogen or another e.g. skin
Topic : Immunity
Specific Defences
Mechanisms that do distinguish between different
pathogens e.g. lymphocytes
Topic : Immunity
Phagocytosis
Pathogens are engulfed into vesicles (called
phagosomes) and broken down by enzymes
Topic : Immunity
Antigens
Part of an organism that is recognised as non-self and
triggers an immune response (usually they are proteins)
Topic : Immunity
Cell-mediated Immunity
T lymphocytes recognise antigen-presenting cells that
have been invaded and undergo mitosis to respond
Topic : Immunity
Humoral Immunity
Immunity involving B cells and antibodies
Topic : Immunity
Antigenic Variability
Viruses such as flu have many different strains with
different antigens on them
Topic : Immunity
Antibodies
Proteins synthesised by B cells, consisting of heavy and
light chains and variable and constant regions
Topic : Immunity
Antigen-Antibody Complex
Formed when antigens bind to a specific site on the
antibody
Topic : Immunity
Complementary Shape
Antigens have a shape that means they fit into their
specific antibody
Topic : Immunity
Monoclonal Antibodies
Isolation and cloning of a single type of antibody
Topic : Immunity
Passive Immunity
The introduction of antibodies from an outside source
Topic : Immunity
Active Immunity
Stimulation of antibody production by the individual’s
own immune system
Topic : Immunity
Vaccination
The introduction of a substance into the body with the
purpose of stimulating active immunity against a
particular disease
Topic : Immunity
Herd Immunity
Vaccinating most of a population so that no-one has the
disease and transmission is stopped
Topic : Variation
Interspecific Variation
Differences between different species
Topic : Variation
Intraspecfic Variation
Differences between members of the same species
Topic : DNA and Meiosis
Nucleotide
Section of DNA made up of sugar, phosphate and a base
Topic : DNA and Meiosis
Complementary
A always bonds to T and C always bonds to G (they are
complementary to each other)
Topic : DNA and Meiosis
Gene
A section of DNA that codes for making a polypeptide
Topic : DNA and Meiosis
Triplet Code
3 bases code for an amino acid
Topic : DNA and Meiosis
Chromosome
Thread-like structure made of protein and DNA, passes
hereditary information on
Topic : DNA and Meiosis
Homologous Chromosomes
2 chromosomes determining the same characteristics
one from mother, one from father
Topic : DNA and Meiosis
Allele
One of the different forms of a gene
Topic : DNA and Meiosis
Meiosis
Cell division that produces 4 haploid (half the
chromosomes), genetically different, daughter cells