key associations 3 Flashcards

1
Q

ovarian mets from gastric carcinoma or breast cancer

A

Krukenberg tumor

mucin-secreting signet-ring cells

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2
Q

ovarian tumor (benign, bilateral)

A

serous cystadenoma

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3
Q

ovarian tumor (malignant)

A

serous cystadenocarcinoma

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4
Q

pancreatitis (acute)

A

gallstones, alcohol

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5
Q

pancreatitis (chronic)

A
alcohol (adults);
cystic fibrosis (kids)
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6
Q

patient w/ ALL / CLL / AML / CML

A

ALL: child
CLL: adult > 60
AML: adult~65
CML: adult 30-60

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7
Q

pelvic inflammatory disease

A

Chlamydia trachomatis, Neisseria gonorrhoeae

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8
Q

Philadelphia chromosome t(9;22) => bcr-abl

A

CML (may sometimes be assoc w/ ALL / AML

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9
Q

pituitary tumor

A

prolactinoma, somatotropic “acidophilic” adenoma

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10
Q

primary amenorrhea

A

Turner syndrome (45,XO)

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11
Q

primary bone tumor (adults)

A

multiple myeloma

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12
Q

primary hyperaldosteronism

A

adenoma of adrenal cortex

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13
Q

primary hyperparathyroidism

A

adenomas, hyperplasia, carcinoma

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14
Q

primary liver cancer

A

hepatocellular carcinoma
(chronic hepatitis, cirrhosis, hemochromatosis,
alpha-1 antitrypsin deficiency)

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15
Q

pulmonary hypertension

A

COPD

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16
Q

recurrent inflammation / thrombosis of small/medium vessels in extremities

A

Buerger’s disease (strongly assoc w/ tobacco)

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17
Q

renal tumor

A
renal cell carcinoma: assoc w/ VHL & smoking;
paraneoplastic syndromes (EPO, renin, PTH, ACTH)
18
Q

right heart failure due to pulmonary cause

A

cor pulmonale

19
Q

S3 (protodiastolic gallop)

A

increase ventricular filling

L to R shunt, mitral regurg, LV failure-CHF

20
Q

S4 (presystolic gallop)

A

stiff / hypertrophic ventricle

aortic stenosis, restrictive cardiomyopathy

21
Q

secondary hyperparathyroidism

A

hypocalcemia of chronic kidney disease

22
Q

sexually transmitted disease

A

chlamydia (usually coinfected w/ gonorrhea)

23
Q

SIADH

A

small cell carcinoma of lung

24
Q

site of diverticula

A

sigmoid colon

25
Q

sites of atherosclerosis

A

abdominal aorta > coronary artery > popliteal artery > carotid artery

26
Q

stomach cancer

A

adenocarcinoma

27
Q

stomach ulcerations & high gastrin levels

A

Zollinger-Ellison syndrome

gastronoma of duodenum or pancreas

28
Q

t(14;18)

A

Follicular lymphomas (bcl-2 activation)

29
Q

t(8;14)

A

Burkitt’s lymphoma (c-myc activation)

30
Q

t(9;22)

A

Philadelphia chromosome, CML (bcr-abl fusion)

31
Q

temporal arteritis

A

risk of ipsilateral blindness due to thrombosis of ophthalmic artery;
polymyalgia rheumatica

32
Q

testicular tumor

A

seminoma

33
Q

thyroid cancer

A

papillary carcinoma

34
Q

tumor in women

A

leiomyoma

estrogen dependent, non precancerous

35
Q

tumor of infancy

A

hemangioma

usually regresses spontaneously by childhood

36
Q

tumor of adrenal medulla (adults)

A

pheochromocytoma (usually benign)

37
Q

tumor of adrenal medulla (kids)

A

neuroblastoma (malignant)

38
Q

type of Hodgkin’s

A

nodular sclerosis (vs mixed cellularity, lymphocytic predominance, lymphocytic depletion)

39
Q

type of non-Hodgkin’s

A

diffuse large cell

40
Q

UTI

A

E. coli, Staphylococcus saprophyticus (young women)

41
Q

Viral encephalitis affecting temporal lobe

A

HSV-1

42
Q

vitamin deficiency (US)

A

Folate

pregnant women are at high risk; body stores only 3-4 month supply; prevents neural tube defects