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protein syn. inhibitors > ketolides > Flashcards

ketolides Flashcards

1
Q

telithromycin

A

semisynthetic

14 membered ring

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2
Q

CH SHaMS BaToon Sa MaLe jool Nahi kerta

A 
chlamydia
h. pylori + h . influenza
s; pyogenes + pneumonia + aureus
Bacteroides fragilis
t. gondii + non tuberculous mycobacterium
mycoplasma + Moraxella catarrhalis
legionella
n. gonorrhea
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3
Q

macrolide resistant strains

A

due structural change

eflux pump does not work

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4
Q

absorption

A

GIT

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5
Q

distribution

A

good

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6
Q

excretion

A

met. - liver

excrete - bile + urine

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7
Q

dose

A

800mg
single dose
daily

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8
Q

respiratory tract inf

A

community acquired pneumonia
sinusitis
acute on bronchitis
streptococcal pharyngitis

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9
Q

contraindication

A

similar to erythromycin

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protein syn. inhibitors (6 decks)

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