Kania - DM Med Contraindications Flashcards

1
Q

HF (NYGC class III and IV)

A

Metformin
DPP-IV (except sitagliptin)
Caution TzDs

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2
Q

Kidney disease

A
Metformin if CrCl<30 mL/min
Metformin half dose and don't initiate if CrCl 30-45 mL/min
Canagliflozin
Dapagliflozin
Sulfonylureas
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3
Q

Liver disease

A

Caution Sulfonylureas
Caution meglitinides
TzDs CI if LFT >/ 2.5x
TzDs D/C LFT > 3x

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4
Q

Osteoporisos

A

Caution canagliflozin

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5
Q

Pancreatitis

A

DPP-IV

GLP-1 Agonist

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6
Q

Joint Pain

A

DPP-IV

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7
Q

Type 1 Diabetes

A

Sulfonylureas

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8
Q

Alcoholism

A

Metformin cautioned

Sulfonylureas cautioned

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9
Q

DKA

A

Metformin
Caution SGLT2 inhibitor
alpha-glucosidase

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10
Q

GI disorder

A

alpha-glucosidase

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11
Q

Thyroid C-cell cancer

A

GLP-1 agonist

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