JUST abx exam 3 lecture 2

Question 1

what bacterias does aminoglycosde kill? specfically gentamycin/tobramycin/amikacin?

Answer 1

gram neg bacilli mainly = both H influenza, K pneoumonia, E.coli, all the bacters (citro,aciento,entero), S.marcescens, P mirabilis , pseudomonas

ALL OF GRAM NEG EXCEPT R/S

Question 2

other than gram neg, what else does aminoglycoside kill or good for?

Answer 2

1. it also does a few gram postive WHEN COMBINED W other drugs
   - L.monocytogenes = AG + amipicllin
   - Endocarditis by enterococci = PCN + gentamin
2. TB, mainly streptomycin
3. surgicla mainly neomycin can wipe out gut floor adding erythromycin will be top notch

Question 3

what are the MANY INDICATION for doxy?

Answer 3

1. URI = S. pneuonima, S pyrogens, S virdines, mycoplasma.punemonia, L.pneumophila
2. MSSA MRSA
3. (-) ONLY H.FLU
4. Rocky mountatin dz
5. mediterranean spotted fever - **R.conorri **
6. anaerboes - peptostrepococci
7. STI: C.trachmatis, T.pallidum

EXTRA IMP:
1. propionibacteria (skin, rosacea, acne)
2. Lyme dz
3. anthrax for 60 days
4. vibrio cholera
5. malaria –>** P.falciparum **
6. brucellosis - from animals and farm
7. intra-abdo infections, enterococci - **tigecycline **

Question 4

which drug casues dental discoloration ?

Answer 4

doxy

Question 5

which drug has both oto and nephrotoxciity?

Answer 5

aminoglycosides

Question 6

what do u give azitrho and erythro and clarithro for?

Answer 6

erythromycin
- Sp, SP, SV, MSSA, MP, LP, S.T chylimmida
- C.dip
- B.pertussis (E and A)

Azithromycin
-SP, SP, SV, MSSA, only H.flu, N.gonnor, MP, LP, S.T chylimadia
- B.pertusis (E and A)

Clarithro
- MAI + azithro
- Hpylori: clarithro, amoxicillin, omepreazole

Both
- acute sinusiits, acute otitis media
- dental prophylaxis (if allergic to pcn)
- C.jejuni (A or E)
- Bartonella hensela - cat scrathcing - E or other macolides
- lyme dz not first in line

Question 7

what does clinda kill?

Answer 7

gram + anaerobes
- - SP SP SV, MSSA, MRSA, pepto, bacteriodes fragilis
- dental if pcn allergcy
- respiratroy abcess?
- skin and soft tissue

Question 8

what bacteris does clorampenicol kill?

Answer 8

• SP, SP, SV
• H,FLU, E,COLI, K.P
• rickets in preg since doxy a big no
• n meningits, n gonorreha
• pepto and bacteroides

Question 9

what bacteria died with linozolid?

Answer 9

• SP SP SV
• MSSA MRSA, S EPIDERMIs
• pepto/baceriodes
• C.diff
• noscomial P, CAP
• L.M
• nocardia
• corynebacteria
• TB

Question 10

what does ciprofloxain kill?

Answer 10

• ALL GRAM - EXCEPT R (including pseudomona, salmonella)
• N.meningits, N.gonorreha
• L.P
  chancord
• UTI - 2nd in line
• bone ostermyletiis and DM foot

Question 11

what does ofloxcin kill?

Answer 11

• salmonella (CO)
  -chlamydia
• prostate and E.coli (NOC)

Question 12

what does levo and moxi kill?

Answer 12

• SP SP SV
• MSSA
  1/2 of gram - such as H.flu, K.puenmo, e.coli, all the bacters, SM, PM
• peptostreptobactera, (bacteridoes <– only moxi)
• MP, LP

Question 13

what does TMP-SMX kill?

Answer 13

1/2 of + and 1/2 - and salmonella
-NOT S.PYROGENS !!!!!
- SP, SV, MSSA, MRSA
- H flue, E.coli, K.P, bacters, SM, PM
- salmonella

extra stuff:
- UTI not first in line
- URI: acute chornic bronchtiis, acute otisis media, acute maxillary sinutitis, pneuocysitic jiroveci
- shigella GI shit

Question 14

what does silver sulfadiazine tx?

Answer 14

burns topically

Question 15

what does sulfadiazine tx?

Answer 15

nocardia - RARE

nocardia is also tx w linozolid remember!

Question 16

what does pyrimethamine tx?

Answer 16

anti malaria and toxoplasam
whoa scary

Question 17

what does nitrofurantonin kill?

Answer 17

– UTI 1st in line causes urine to be brown = normal
- enterococcio gram + = e.faecalis
- gram - = e.coli, kp, H flue, bacters, SM, PM

Question 18

what does fosfomycin kill?

Answer 18

UTI!!! caused by e coli, entercocci.facecalis