Joints, Synovial Fluid and Cartilage Flashcards

1
Q

What are the three types of joints?

A

Fibrous, Cartilaginous and Synovial

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2
Q

Where can fibrous joints be found?

A

The skull, periodontal ligaments, interosseus membranes

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3
Q

Where can cartilaginous joints be found?

A

Growth Plates (synchondrosis aka primary cartilaginous joints - only hyaline)

Intervertebral Discs (Symphysis joint aka secondary cartilaginous - hyaline and fibrocartilage)

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4
Q

What are the features of synovial joints?

A
  • Synovial cavity, articular cartilage, fibrous capsule, synovial membrane
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5
Q

What are the types of synovial joints?

A

Plane, Condylar, Hinge, Saddle, Pivot, Ball and Socket

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6
Q

What influences joint stability?

A

Shape of articulating surfaces, capsule and ligaments, muscles

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7
Q

What are the types of cartilage within a synovial joint?

A

Hyaline and Fibrocartilage

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8
Q

Describe the histology of hyaline cartilage?

A

Superficial layer - flattened chondrocytes that produce collagens and glycoproteins

Transitional Layer - round chondrocytes that produce proteoglycans

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9
Q

What are glycoproteins ?

A

Proteins to which oligosaccharide chains are attached

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10
Q

What are proteoglycans ?

A

Proteins that are heavy glycosylated

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11
Q

What are glycosaminoglycans?

A

Long unbranched polysaccharides which are highly polar and thus attract water

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12
Q

What is the average thickness of hyaline cartilage?

A

Average :2-3mm

Interphalangeal Joint -1mm

Patella - 5-6mm

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13
Q

What is synovial fluid produced by?

A

Synoviocytes within synovium

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14
Q

What occurs at synovium?

A

Direct exchange of oxygen, carbon dioxide and metabolites between blood and synovial fluid

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15
Q

Describe Type A synoviocytes?

A

Look like macrophages, remove debris, contributes to synovial fluid production

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16
Q

Describe Type B synoviocytes?

A

Fibroblast like and main producer of synovial fluid

17
Q

Describe synovial fluid?

A

Viscous fluid containing hyaluronic acid and lubricin

18
Q

What is the function of synovial fluid?

A

Nutrition of cartilage, removal of waste products

Lubrication = less friction and less wear

19
Q

Describe the process of lubrication?

A

Boundary
- glycoproteins bind to receptors on articular surfaces to form a thin film

Hydrodynamic

  • Surfaces are kept apart by liquid pressure
  • Viscosity changes with load and velocity of movement

Weeping
- Fluid that is present in the cartilage is squeezed out into synovial cavity to increase fluid volume

20
Q

What are bursae?

A

Fluid filled sacs which reduce friction

21
Q

What occurs to synovial fluid and cartilage with ageing?

A

Increased viscosity of synovial fluid = slower joint movements, reduced lubrication

Water content of cartilage decreases and reduces shock absorption