JC - Motor Systems Flashcards
Do muscles actively shorten or elongate?
Muscles only ever actively shorten
- One muscle shortens to create a movement, another muscle shortens to return it back to its original position
What does one muscle cell/fibre contain? (2)
- Myofibrils
- Sarcolemma
What are myofibrils composed of?
Sarcomeres
What are the 2 main myofilaments?
Actin and Myosin
What is the function of T-tubules in terms of action potentials?
T-tubule runs into the muscle allowing for action potentials to be generated closer to the internal site
What are T-tubules bound to?
Bind to voltge gated calcium channel which binds to Sarcoplasmic Reticulum
What are the 3 types of muscle contraction?
-
Isometric:
Load = Force (muscle) -
Concentric:
Load < Force (muscle) -
Eccentric:
Load > Force (muscle)
What are the 7 steps involved in the neuromuscular junction?
- The action potential travels along myelinated motor neurone
- Calcium enters motor neurone
- Vesicles of Acetylcholine fuse to the motor neurone membrane
- Acetylcholine diffuses across the extracellular matrix
- Ligand-gated channels activate allowing substantial sodium to enter the cell and some potassium to exit
- Voltage-gated sodium channels open along the sarcoplasmic membrane
- Calcium is released into the sarcoplasmic reticulum
What is the benefit of working extracellularly?
Less likely to damage the cell
When are muscles stronger?
- Muscles are stronger at an eccentric contraction (longer muscle)
- Muscles are stronger when they are moving slower