Jaundice Flashcards

1
Q

Why does jaundice appear in skin and sclera?

A

Because they contain elastin which has high affinity for bilirubin

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2
Q

Normal level of bilirubin in plasma……

A

0.3-1mg/dl

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3
Q

…….is called hyperbilirubinemia

A

1-2mg/dl

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4
Q

Bilirubin above 2mg/dl is

A

Jaundice

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5
Q

Jaundice can be classified according to…….

A

Type of bilirubin

Anatomical site of defect

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6
Q

Pre-hepatic jaundice is due to…..

A

Increased hemolysis

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7
Q

Normal stool and urine color in ……. Jaundice

A

Pre-hepatic

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8
Q

Type of bilirubin elevated in hepatic jaundice

A

Direct and indirect

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9
Q

Urobilinogen is absent in …… jaundice

A

Post-hepatic

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10
Q

Kernicterus occurs when bilirubin is above……

A

20-25mg%

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11
Q

Only…….bilirubin can cross BBB in neonates

A

Unconjugated

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12
Q

Ttt of neonatal jaundice

A

Phototherapy

Phenobarbital

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13
Q

……….is not affected by phenobarbital

A

Crigler-Najjar syndrome type 1

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14
Q

Cause of Gilbert syndrome

A

Deficient glucuronyl transferase enzyme

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15
Q

……..is characterized by complete absence of glucuronyl transferase

A

Type 1 of Crigler-Najjar syndrome

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