Bile Acids And Salts

Question 1

What are steroids?

Answer 1

They are compounds having a steroid nucleus
Ex: cholesterol 27 C
      Bile acids 24 C
      Steroid hormones
      Plant sterol 28 C

Question 2

The ……of cholesterol can’t be metabolized in the body

Answer 2

Ring structure

Question 3

How is the intact sterol nucleus eliminated from the body?

Answer 3

1. Conversion to bile salts and bile acids

2. Small percentage excreted in stool as coprastanol

Question 4

Main components of bile

Answer 4

Bile acids and salts
Lecithin
Cholesterol
Bile pigments

Question 5

Hydroxyl group is…….and lies in ……. orientation

Answer 5

Polar , alpha

Question 6

Methyl groups are……and lie in…… orientation

Answer 6

Non polar, beta

Question 7

……… Act as emulsifying agents

Answer 7

Bile acids and bile salts

Question 8

Rate limiting enzyme of bile acid synthesis

Answer 8

7 alpha hyroxylase enzyme

Question 9

Expression of 7 alpha hyroxylase enzyme is …….by bile salts

Answer 9

Down regulated

Question 10

Ratio of Glycine:taurine forms

Answer 10

3:1

Question 11

1ry bile acids

Answer 11

Cholic acid and chenodeoxycholic acid

Question 12

Taurine is

Answer 12

End product of cysteine

Question 13

…….makes salts more effective emulsifying agents than acids

Answer 13

Their enhanced amphipathic nature

Question 14

2ry bile acids

Answer 14

Deoxycholic acid from cholic acid

Lithocholic acid from chenodeoxycholic acid

Question 15

Bile acid sequestrants

Answer 15

Cholestyramine

Dietary fibre