Jaundice Flashcards
1
Q
Jaundice
A
Yellow discolouration of skin due to excess bilirubin
2
Q
Pre-Hepatic jaundice
A
Excess bilirubin production via:
Haemolytic anaemia
Ineffective erythropoiesis e.g. thalassaemia
Unconjugated bilirubin
3
Q
Hepatic jaundice
A
Mix of conjugated and unconjugated bilirubin
Causes: Drugs: contrast, Rifampicin Gilbert’s (AD), antimalaria Wilson's disease Haemochromatosis Hepatitis B+C Autoimmune hepatitis CLD - cirrhosis
4
Q
Neonatal jaundice
A
Physiological
↑ production + ↓ conjugation
5
Q
Post hepatic jaundice
A
Conjugated bilirubin
Dark urine + pale floating stools
Obstruction: Stones Ca pancreas head PBC PSC Choledochal cyst Cholangio Ca
6
Q
Ix
A
Abdo exam Basic obs Bloods: - bilirubin - FBC - ALT - AST - ALP - Clotting factors - PT - Albumin - GGT Urine sample Antibody test - Hepatitis Abdo USS - obstruction
