Hepatitis Flashcards
Why hepatitis type is caused by a DNA virus
Hepatitis B
Transmission of each hepatitis
A - faeco - oral B - sexual, vertical, parenteral C - parenteral (IVDU) D - parenteral, sexual E - faeco oral
Which hepatitis can be passed from mother to baby
Hepatitis B
Which hepatitis is chronic
Hepatitis C
Risk factor of hepatitis A
Travelling to Asia or Africa
Clinical feature of hepatitis
Symptoms RUQ pain Pruritis Nausea and vomiting Anorexia Joint pain
Signs:
RUQ tenderness
Jaundice
Flu symptoms
Investigations
Abdominal examination
Obs
Bloods - LFTs, U+Es, FBC, CRP, prothrombin time, serology
Serology
Surface antigen - active infection
Surface antibody - immunity - past infection or vaccinated
Core IgM - acute infection
Core IgG - past infection
e antigen - infectious - active replication
Vaccinated serology
Surface antigen - negative
Surface antibody - positive
IgM - negative
IgG - negative
Chronic infection serology
Surface antigen - positive
Surface antibody - negative
IgM - negative
IgG - positive
Immune last infection serology
Surface antigen - negative
Surface antibody - positive
IgM - negative
IgG - positive
Acute infection serology
Surface antigen - positive
Surface antibody - negative
IgM - positive
IgG - positive
Definition of chronic hepatitis
Hepatitis lasting for 6 months or longer
Management of hepatitis
A - supportive care
B - antivirals - pegylated IFN- a (no cure)
C - antivirals +/- ribaviran
Hepatitis E risk factors
Farm animals
Immunocompromised