Ascending Cholangitis Flashcards

1
Q

Charcot’s triad

A

RUQ pain
Jaundice
Fever

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2
Q

Presentation

A

RUQ pain - biliary colic
Fever
Jaundice

Pruritis
Pale stools

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3
Q

Reynold’s Pentad

A

Charcot’s triad + hypotension + confusion

  • indicative of severe ascending supportive cholangitis
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4
Q

Investigations

A
Abdominal examination 
Obs 
Bloods - FBC, U+Es, LFTs, CRP
Abdo USS 
ERCP - gold standard 
MRCP
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5
Q

Management

A

Analgesia
IV abx - broad spectrum until future returns - Tazocin
Maintenance fluids

Non operative - ERCP +/- sphincterotomy + drainage stent
Operative - cholecystectomy

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6
Q

When to operate or biliary decompression via ERCP

A

If symptoms persist despite abx and intensive management

Within 24 - 48 hrs after admission

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7
Q

If unfit for ERCP

A

Percutaneous trans - hepatic cholangiography

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8
Q

Pathophysiology

A

Inflammation and infection of the biliary tract can be due to stone in common biliary duct

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9
Q

Complications

A

Acute pancreatitis

Inadequate drainage

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10
Q

Typical causative organism

A

E. Coli

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