Ascending Cholangitis Flashcards
Charcot’s triad
RUQ pain
Jaundice
Fever
Presentation
RUQ pain - biliary colic
Fever
Jaundice
Pruritis
Pale stools
Reynold’s Pentad
Charcot’s triad + hypotension + confusion
- indicative of severe ascending supportive cholangitis
Investigations
Abdominal examination Obs Bloods - FBC, U+Es, LFTs, CRP Abdo USS ERCP - gold standard MRCP
Management
Analgesia
IV abx - broad spectrum until future returns - Tazocin
Maintenance fluids
Non operative - ERCP +/- sphincterotomy + drainage stent
Operative - cholecystectomy
When to operate or biliary decompression via ERCP
If symptoms persist despite abx and intensive management
Within 24 - 48 hrs after admission
If unfit for ERCP
Percutaneous trans - hepatic cholangiography
Pathophysiology
Inflammation and infection of the biliary tract can be due to stone in common biliary duct
Complications
Acute pancreatitis
Inadequate drainage
Typical causative organism
E. Coli