Cholangiocarcinoma Flashcards
1
Q
Pathogenesis
A
Biliary tree malignancy
- mostly adenocarcinomas
2
Q
Presentation
A
Mostly insidious
- weight loss
- pruritis
- Charcot’s triad
- dark urine pale stools
- cachexic
3
Q
Investigations
A
Abdominal examination Obs Bloods - LFTS (ALP raised) , U+Es, FBC, CA 19 -9 ERCP with brushing - gold standard Staging CT
4
Q
Management
A
Depends on stage and site
- lesion excision
- partial liver resection
- if very distal - Whipple’s procedure
Adjunctive chemotherapy or radiotherapy
5
Q
If unresectable
A
Transplant
6
Q
Complications
A
Cholangitis
Biliary leakage
