IV theory workshop Flashcards

(41 cards)

1
Q

what are moles?

A

A mole is a standard quantity
short for 6.02 x10^23
or
the number of atoms in 12g of carbon 12

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2
Q

What number is avogadros constant?

A

6.02 x10^23

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3
Q

What can you measure solvent in?

A

weight or volume

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4
Q

What can you measure solutes in?

A

weight

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5
Q

what is it called when you add solutes to a solvent?

A

A solution

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6
Q

How can you measure concentration of a solution?

A

Lots of ways but main 2

  1. Moles of solute per volume of solution
  2. Moles of solute per weight of solvent
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7
Q

What is Molarity?

A

The number of moles of solute per Liter of solution.
Unit is M

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8
Q

What is Molality?

A

The number of moles of solute per Kg of solvent.
Unit is m

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9
Q

Molarity or Molality? for Moles/L

A

Molarity (M)

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10
Q

Molarity or Molality? for Moles / kg

A

Molality (m)

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11
Q

How to remember the difference between Molality and molarity?

A

MolaRity = moles per LiteR

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12
Q

What is the osmotic pressure determined by?
what has no effect?

A

The number of particles in the solution

size, shape or charge has no effect

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13
Q

What do osmolarity and osmolality refer to?

A

The concentration of all the particles that contribute to osmotic pressure

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14
Q

What is osmolarity?

A

The measure of solute concentration per unit volume of solution
Unit = Osm/L

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15
Q

What is Osmolality?

A

The measure of solute concentration per unit mass of solvent.
Unit = Osm/kg

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16
Q

What is a common example of osmolarity?

A

volume of blood

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17
Q

Why is osmolality different from osmolarity?

A

Osmolality is more accurate and independent of pressure and temperature

18
Q

How is osmolarity calculated?

A

From the CMP - comprehensive metabolic panel

19
Q

How is osmolality measured?

A

measured with a osmometer which measures depression of freezing points

20
Q

what is the osmolarity calculation?

A

Osmolarity = osmolality x 0.995

21
Q

What is tonicity?

A

the measurement of the osmotic pressure gradient between 2 solutions

22
Q

Describe the Solutes in a hypertonic solution compared to the cell?

A

More solutes in the solution comparedto the cell

23
Q

Definition of hypertonic?

A

Higher strength

24
Q

Describe the Solutes in a hypotonic solution compared to the cell?

A

Less solutes in the solution compared to the cell

25
Definition of hypotonic?
Lower strength
26
Describe the Solutes in a isotonic solution compared to the cell
Equal number of solutes in the solution as the cell
27
Definition of Isotonic?
same strength
28
Where does water always move?
Water always follows the solute
29
What happens to water in a hypertonic solution?
water moves out of the cell so it shrinks (crenate)
30
What happens to water in a hypotonic solution?
Water moves into the cell so the cell swells or bursts (turgor or lysis)
31
What happens to water is a isotonic solution?
No net movement so no change to the cell.
32
What are bodily examples of hypertonic solutions?
pulmonary oedema fluid overload
33
What are bodily examples of hypertonic solutions?
Diabetic ketoacidosis (DKA) Hyperosmolar hyperglycemia
34
When do we want to give patients isotonic solutions?
Dehydration , post-op, during hemorrhage and with D and V
35
What does viscosity refer to?
To a substances resistance to flow
36
What is low viscosity?
Little resistance to flow flows quickly and easily
37
What is high viscosity?
Strongly resists flow flows very slowly
38
What is an anaphylactoid?
The term anaphylactoid to describe a non-immune mediated reaction is no longer used. These reactions are described as non-immunologic anaphylaxis and can still be life-threatening.
39
What is IgE - mediated reaction?
This is the classic definition of anaphylaxis, where an allergen activates mast cells and basophils through IgE receptors
40
What is an non-IgE mediated reaction
This pathway can cause symptoms similar to classic anaphylaxis, and can be triggered by a number of factors, including: Antibodies against IgE or their receptors Anaphylatoxins G-coupled receptors IgG antibodies that activate neutrophils Inflammatory mediators like bradykinin or prostaglandin
41
What are the key toxic effects that can be seen after giving IV contrast ?
vascular soft tissue cardio-vascular hematological nephro-toxicity thryroid