IV Medications Flashcards
When is a central line required?
highly concentrated drugs
long-term abx
toxic drugs that can cause phlebitis (chemo)
drugs with pH or osmolarity different to the bloods (parenteral nutrition)
Where does a PICC line empty?
into the superior vena cava
what is a vesicant?
a drug that can cause severe tissue damage if the catheter tip falls out of the vein
What types of drugs are vesicants?
vasopressors, anthracyclines (doxorubicin), vinca alkaloids, digoxin, foscarnet, nafcillin, mannitol, promethazine
How should promethazine be administered
Via central line! Vesicant!
What are some guides on iv compatibility
Trissel’s
King’s
Examples of chemical incompatibility
hydrolysis
oxidation
decomposition
What is DEHP
a plasticizer that can leach into drugs and is toxic
What can be used as an alternative to PVC containers to avoid leeching
polyolefin
polypropylene
glass
What are some key drugs that have compaitibility issues with PVC
Leaches Absorb To Take In Nutrients Lorazepam Amiodarone Tacrolimus Taxanes Insulin Nitroglycerin
Drugs that require saline as a diulent
A DIAbetic Can't Eat Pie Ampicillin Daptoycin Infliximab Amp/Sulbactam Caspofungin Ertapenem Phenytoin
Durgs than require dextrose diulent
BOAS with strangle the pharmacist that puts this drugs in anything that isn't dextrose Bactrim Oxalplatin Amphotercin B Synercid
what compatibility issues occurs with ceftriaxone
CANNOT be mixed with calcium
Can ceftriaxone mix with lactated ringers?
NO! LR’s contain calcium
Which two items are notorious for forming percipitates when mixed?
calcium and phosphorus
what filter size is used for lipids?
1.2 microns
what filter size is used for parenteral nutrition
0.22 microngs
Key drugs that require filters
that's my GAL, PAT who's head is flat Golimumab Amiodarone Lorazepam Phenytoin Lipids Amphotericin B Taxanes
What IV drugs should not be refridgerated
Dear Sweet Pharmacist, Freezing Makes Me Edgy Dexmedetomidine Sulfameth/Trimethoprim Phenytoin Furosemide Metronidazole Moxiflox Enoxaparin
What drug comes as a blue IV fluid
Mitoxantrone
What drugs come as red IV fluid
anthracyclines
rifampin
