IUGR, Size, Fluid Flashcards
what does IUGR stand for?
Intrauterine growth restriction
What is IUGR and what is it caused by?
growth retardation in utero due to pathology therefore not reaching genetic potential
What does SGA stand for and what is it?
small for gestational age
<10th centile fetal growth
+/- pathological
Causes of IUGR?
foetal 3CS - chromosomal abnormalities, congenital abnormalities and congenital infection
Maternal - HTN, Placental insufficiency, aPL, smoking, poorly controlled DM
IUGR can be …. or …..
symmetrical or asymmetrical
Symmetrical %?
fetal or maternal?
abdo and brain affected?
mental problems?
30%
fetal deficits
abdo and brain proportionally affected growth
yes mental problems (delays)
Asymmetrical %?
fetal or maternal?
abdo and brain affected?
mental problems?
70%
Maternal placental insufficiency
Abdo and peripheral retardation
No brain involvement
no mental changes (no delay)
Comps of IUGR?
premature, still birth, cognitive delays
the 2 sizes a baby can be?
LGA large for gest age
SGA small for gest age
what does SGA + LGA mean ?
macrosomia
>90th centile for weight (>4.5kg)
<10th centile (<2.5kg)
LGA
Cause?
Ix?
Complications?
idiopathic , fHx (constitutional), Gest dm, polyhydromnios, post term
Regular USS
OGTT 24-28 WKS
Perineal tears, shoulder dystocia, PPH
SGA
Cause?
Idiopathic
fHx
placental insufficiency
congenital infection
chromosomal abnormality
What is shoulder dystocia?
when the baby’s shoulder is stuck behind the maternal pubis symphysis
MC complication of shoulder dystocia?
Erbs palsy
arm/shoulder muscle weakness
What is the treatment for shoulder dystocia?
Help
McRoberts maneuvre
Pressure on suprapubic area
episiotomy
Enter (internal rotation)
roll on all 4s
What are the 2 types of fluid levels and %?
Polyhydromnios (1-2%)
Oligohydromnios (6%)
What is polyhydromnios?
Causes?
Exam?
Comps?
AFI (amniotic fluid index) >25 (>25cm) on USS, >2000ml
Causes - gest dm, atresia (oesophageal + duodenal deficit), TORCH
Exam - high SFH, Lack of foetal HB, indistinct features, fluid thrill
Cord prolapse, placental abruption, PPH, high risk UTI, stillbirth, premature
What is oligohydromnios?
Causes?
Exam?
Comps?
AFI <5 (<5CM) <300ml
Causes- PPROM, Potter sequence (abnormal kidney growth + function due to low amniotic fluid), uteroplacental insufficiency
low SFH, Prominant features
comp - fetal deformity/IUGR, still birth, premature, chorioamnionitis
Vomiting occurs in % of pregnancies?
Is it common and why?
When does it resolve?
80%
very common in 1/3 due to high beta hCG from syncytiotrophoblast
resolves by 16-20 weeks normally
What is non severe and severe vomiting called in pregnancy?
Nausea and vomiting of preg - NVP
hyperemesis gravidarum
RF for vomiting in preg?
Multiple pregnancies
molar preg
hyperthyroid
DKA
Sx of hyperemesis in preg?
RCOG triad:
5% or more pre pregnancy wt loss
Dehydration (low turgor, pallor, thirst)
Electrolyte imbalance (ketoamine)
(+ decreased appetite, severe vomiting)
Dx of hyperemesis gravidarum?
bloods (FBC, U+E, LFT, TFT, Clotting)
OGTT
Urine dip
TV USS + Serum bhCG (RULE OUT MOLAR)
BP, BMI, ECG
VBG
What would be seen on VBG?
hypoK+
hypoCl-
metabolic alkalosis
What is used to classify the severity of NVP?
PUQE
Pregnancy unique quantification of emesis
1st line treatment for Emesis?
Antihistamine (cyclizine or promethazine)
or
Phenothiazines (prochlorperazine or Chlorpromazine)
or
Comnination drug (doxylamine/pyridoxine - xonvea)
2nd line Tx for emesis?
Ondansetron
What is ondansetron?
max time to take It for and why?
5-HT3 receptor antagonist
max 5 days due to high risk of cleft lip/palate in 1/3
3rd line Tx for emesis?
Metoclopramide
or
Domperidone
Metoclopramide
What type of medication is it?
max time to take it for and why?
how does it work?
Dopamine receptor antagonist (DA2R-i)
Max 5 days due to extra pyramidal side effects (EPSE)
ACTS centrally in chemoreceptor trigger zone by crossing BBB)
Domperidone
What type of medication is it?
max time to take it for and why?
how does it work?
dopamine receptor antagonist
max 7 days due to increased cardiovascular arrhythmias risk
peripheral D2+3R-i therefore decrease GI motility
Other Tx for NVP?
Ginger
Acupuncture
Hypnosis
Complication of NVP?
Tx for this?
Dehydration
advice oral fluid rehydration, or last resort IV
Other complications of vomiting?
MW tear
Hypo K+
hypotension