ischemic heart disease Flashcards
Ischemic heart disease definition
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Risk factors for developing CAD
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Preoperative assessment
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Preoperative orders
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Angina pectoris
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Diagnosis angina
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Chest pain differential
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Stable vs Unstable Angina
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Acute coronary syndrome (MI)
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Morbidity/Mortality Risks- longer wait after MI the better (for remodeling)
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•12 lead EKG
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•Exercise angina
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•Nuclear stress imaging
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•Echocardiography
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•Coronary angiography- that we have and where plus distal targets
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Vulnerable plaque
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Treatment of CAD
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Treatment of CAD
Lowering LDL: “Statins”
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Statin concerns…
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New way to lower LDL- injection
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Lowering Hypertension:
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Classes of Platelets
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Aspirin
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Thienopyridines
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Platelet glycoprotein receptor inhibitors
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Nitrates
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Do nitrates dilate atherosclerotic coronary arteries?
A little bit depending on level of atherosclerosis and size of coronary artery
How do nitrates decrease left ventricular afterload?
Closed loop: decreased CO would decrease afterload
Beta-blockers
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Beta blockers and mortality after MI-
older 30-50% reduction; younger is like 20%
How do beta-blockers increase coronary artery perfusion?
Increases perfusion time because the ostea of the coronary arteries are occluded during systole and coronary vessels collapse during systole
Calcium Channel Blockers
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ACEI/ARB
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ACE inhibitors
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Indications of PCI
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Mechanics of stent placement
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DAPT: dual anti-platelet therapy (aspiring and something else)
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BMS/DES algorithm
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Progress…..
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Anesthesia considerations
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When to stick, catheter/puncture???
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