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ISBB Flashcards

1
Q

THE STUDY OF A HOST REACTION WHEN FOREIGN SUBSTANCES ARE INTRODUCED INTO THE BODY.

A

IMMUNOLOGY

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2
Q

CONDITION OF BEING RESISTANT TO INFECTION

A

IMMUNITY

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3
Q

PRACTICE OF INHALING POWDER MADE FORM SMALLPOX SCABS

A

VARIOLATION

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4
Q

DISCOVERED SMALLPOX VACCINATION

A

JENNER

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5
Q

DISCOVERED LIVE ATTENUATED CHICKEN CHOLERA AND ANTHRAX VACCINES

A

PASTEUR

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6
Q

FATHER OF IMMUNOLOGY

A

PASTEUR

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7
Q

DEMOSTRATION OF CUTANEOUS HYPERSENSITIVITY

A

KOCH

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8
Q

DISCOVERED POLIO VACCINE

A

SALK AND SABIN

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9
Q

LINKED TWWO THEORIES “CELLULAR AND HUMORAL”

A

ALMOTH WRIGHT

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10
Q

ANTIGEN WAS INTRODUCED EXAMPLE IS INFECTION

A

NATURAL ACTIVE

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11
Q

ANTIGEN WAS INTRODUCED EXAMPLE IS VACCINE

A

ARTIFICIAL ACTIVE

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12
Q

ANTIBODY WAS INTRODUCED EXAMPLE IS RHOGRAM

A

ARTIFICIAL PASSIVE

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13
Q

ANTIBODY WAS INTRODUCED EXAMPLE IS AB THAT CNA CROSS TO PLACENTA

A

NATURAL PASSIVE

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14
Q

DOMINANT AND 1ST TO ARRIVE THEN SELF DESTRUCT

A

NEUTROPHIL

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15
Q

BLOOD TO TISSUE BY FORMING PSEUDOPODS

A

DIAPEDESIS

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16
Q

INCREASE IN ALLEGY AND PARASITIC INFECTION

A

EOSINOPHIL

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17
Q

NEUTRALIZE BASOPHIL AND MAST CELL

A

EOSINOPHIL

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18
Q

MEDIATES ANAPHYLAXIS

A

BASOPHILS

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19
Q

LARGER, LONGER LIFE SPAN AND DIFFER IN ENZYME CONTENT

A

MAST CELLS

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20
Q

CYTOKINES THAT ACTIVATE MACROPHAGE

A

IFN-Y
G-CSF

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21
Q

TERMINAL STAGE OF MONONUCLEAR PHAGOCYTE DEVELOPMENT

A

MULTINUCLEAR GIANT CELLS

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22
Q

MACROPHAGES RELEASE___ DURING ANTIGEN PROCESSING

A

IL-1
IL-6

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23
Q

LIPID DISORDER THAT IS DEFICIENT IN B-GLUCOCEREBROSIDASE
WRINKLED CYTOPLASM

A

GAUCHER’S

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24
Q

DEFICIENCY OF SPHINGOMYELINASE
FOAMY CYTOPLASM

A

NIEMANN-PICK DISEASE

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25
Q

MOST POTENT ANTIGEN PRESENTING CELL IN THE TISSUE

A

DENDRITIC CELLS

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26
Q

WHAT IS THE STIMULUS OF APR?

A

IL-6

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27
Q

WHAT IS THE MAIN SUBSTRATE OF CRP

A

PHOSPHOCHOLINE

28
Q

FUNCTION OF THIS PROTEIN IS OPSONIZATION, COMPLEMENT AND ACTIVATION

A

CRP

29
Q

FUNCTION OF THIS PROTEIN IS REMOVAL OF CHOLESTEROL

A

SERUM AMYLOID A

30
Q

FUNCTION OF THIS PROTEIN IS PROTEASE INHIBITOR

A

ALPHA 1 ANTITRYPSIN

31
Q

FUNCTION OF THIS PROTEIN IS CLOT FORMATION

A

FIBRINOGEN

32
Q

FUNCTION OF THIS PROTEIN IS BINDS TO HEMOGLOBIN

A

HAPTOGLOBIN

33
Q

FUNCTION OF THIS PROTEIN IS BINDS TO COPPER

A

CERULOPLASMIN

34
Q

FUNCTION OF THIS PROTEIN IS OPSONIZATION, LYSIS

A

COMPLEMENT C3

35
Q

USED TO MONITOR HODGKIN DISEASE

A

CERULOPLASMIN

36
Q

USED FOR DIFFERENTATION BETWEEN VIRAL AND BACTERIAL INFECTION

A

CRP

37
Q

WHAT IS THE SEQUENCE OF PHAGOCYTOSIS

A

ICEE
INGESTION
CHEMOTAXIS
ENGULFMENT AND DIGESTION
EXOCYTOSIS

38
Q

DUSCOVERED IN THE FRUITFLY

A

TOLL-LIKE RECEPRTOR

39
Q

TLR FOR GRAM +

A

TLR 2

40
Q

TLR FOR GRAM NEG

A

TLR 4

41
Q

TLR 1 IS FOR

A

MYCOBACTERIA

42
Q

ENHANCES PHAGOCYTOSIS

A

OPSONIN

43
Q

EXAMPLES OF OPSONIN

A

C.A.C
CRP
ANTIBODY
COMPLEMENT

44
Q

IMMUNE CELLS MIGRATE TO THE SITE OF INFLAMMATION

A

CHEMOTAXIS

45
Q

ATTRACTED TO THE SITE OF INJURY BY THE CHEMOTAXINS

A

NEUTROPHIL

46
Q

MIGRATE SEVERAL HOURS AFTER AND ACT AS SCAVENGER

A

MACROPHAGE

47
Q

CHEMICAL MESSENGER THAT CAUSE CELLS TO MIGRATE IN PARTICULAR DIRECTION

A

CHEMOTAXINS

48
Q

NORMAL MOVEMENT BUT POOR DIRECTIONAL MOTILITY

A

JOB SYNDROME

49
Q

RANDOM MOVEMENT AND DOES NOT RESPONSE TO CHEMOTACTIC FACTOR

A

LAZY LEUKOCYTE

50
Q

DEFICIENCY IN CHEMOTAXIN

A

TUFSTIN DEFICIENCY

51
Q

DEF IN CYTOSKELETAL PROTEIN

A

ACTIN DYSFUNCTION

52
Q

ADHESION PROBLEM

A

STEROID USE

53
Q

ASSESS THE CHEMOTACTIC RESPONSE OF NEUTROPHIL

A

BOYDEN CHAMBER

54
Q

LYMPHOCYTE CHEMOTATCTIC FACTORS PRODUCTION ABILITY

A

MIGRATION INHIBITION

55
Q

ENHANCES PHAGOCYTOSIS

A

ACETYLCHOLINE

56
Q

INTERNALIZE SURFACE MEMBRANE

A

PHAGOSOME

57
Q

CENTRAL KILLING OF MICROBES

A

NADPH OXIDASE

58
Q

DEFICIENT NADPH OXIDASE

A

CHRONIC GRANULOMATOUS DISEASE

59
Q

MOST IMPORTANT AGENT IS NECESSARY FOR PRODUCING THE TOXIC SUPEROXIDASE THAT ARE CRITICAL IN BACTERIAL KILLING

A

HYDROGEN PEROXIDE

60
Q

MOST IMPORATNT MECHANISM OF BACTERIAL KILLINGH

A

H2O2- HALIDE-MYELOPEROXIDASE SYSTEM

61
Q

PRIMARY GRANULES OF NEUTROPHILS IS DECREASE OR ABSENT

A

MPO DEFICIENCY

62
Q

ACCOUNTS FOR GREENISH COLOR OF THE PUS

A

MPOase

63
Q

DEC IN THE AMOUNT OF HYDROGEN PEROXIDE PRODUCED

A

G6PD

64
Q

ABNORMAL FUSION OF PRIMARY GRANULES IN NEUTROPHILS

A

CHEDIAK-HIGASHI SYNDROME

65
Q

SIRS OR SYSTEMIC INFLAMMATION RESP. SYNDROME + INFECTION

A

SEPSIS

66
Q

SEPSIS + ORGAN DYSFUNCTION

A

SEVERE SEPSIS

ISBB (6 decks)

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