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ISBB > IS DAY 2 > Flashcards

IS DAY 2 Flashcards

1
Q

factors that influencing the immune response

A

OVERALL HEALTH
GENETI DISPOSITION
AGE

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2
Q

SHAPE OR CONFIGURATION THAT ARE RECOGNIZED BY THE T CELL AND B CELL

A

EPITOPE

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3
Q

ANTIGEN,IMMUNOGEN OR HAPTEN

BINDS WITH ANTIBODY

A

ANTIGEN AND IMMUNOGEN

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4
Q

ANTIGEN,IMMUNOGEN OR HAPTEN

EVOKE IMMUNE RESPONSE

A

IMMUNOGEN

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5
Q

ANTIGEN,IMMUNOGEN OR HAPTEN

NEEDS A CARRIER PROTEIN (ALBUMIN) TO CREATE ANTIGENIC DETERMINANT

A

HAPTEN

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6
Q

TRAITS OF IMMUNOGENS/ PHYSICAL NATURE OF ANTIGENN

A

SIZE/WEIGHT
CHEMICAL COMPOSITION ADN COMPLEXITY
FOREIGNNESS
STRUCTURAL STABILITY
ABILITY TO BE PROCESSED AND PRESENTED WITH MHC

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7
Q

Large dose of immunogen+ memory cells= nonresponsive

A

T AND B CELL TOLERANCE

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8
Q

RELATIONSHIP OF ANTIGEN TO THE HOST CELL
SAME INDIVIDUAL

A

AUTOANTIGEN

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9
Q

RELATIONSHIP OF ANTIGEN TO THE HOST CELL
SAME SPP DIFFERENT INDIVIDUAL

A

ALLO ANTIGEN

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10
Q

RELATIONSHIP OF ANTIGEN TO THE HOST CELL
DIFFERENT SPP DIFFERENT INDIVIDUAL

A

HETEROANTIGEN

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11
Q

THERE IS A CROSS REACTIVITY

A

HETEROPHILE

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12
Q

INCREASE IMMUNE RESPONSE BY PRODUCING LOCAL INFLAMMATION

A

ADJUVANT

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13
Q

KILLED MYCOBACTERIA BUT PRODUCES GRANULOMAS OR SCAR TISSUE

A

FREUND COMPLETE ADJUVANTSS

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14
Q

THE ONLY ADJUVANT APPROVED FOR CLINICAL USE IN THE US

A

ALLUMINUM SALTS

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15
Q

VACCINE FOR SMALLPOX AND BCG

A

LIVE

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16
Q

TYPE OF VACCINE FOR INFLUENZA

A

LIVE ATTENUATED

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17
Q

TYPE OF VACCINE FOR CHOLERA AND TYPHOID

A

DEAD

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18
Q

TYPE OF VACCINE FOR CLOSTRIDIUM TETANI AND DIPHTHERIA

A

TOXOID

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19
Q

TYPE OF VACCINE FOR POLIO VACCINES

A

MODIFIED VIRUS

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20
Q

DISCOVERED AN ANTIBDY RESPONSE TO CICULATING WBC

A

FRENCH DAUSSET

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21
Q

MCH. OR FLA IS SYNTHESIZED IN

A

ROUGH ER

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22
Q

THE MOST POLYMORPHIC SYSTEM

A

MHC/ HLA

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23
Q

2ND TO. ANP IN INFLUENCING GRAFT SURVIVAL/REJECTION

A

HLA

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24
Q

LOCATION: ALL NUCLEATED CELL

A

CLASS 1

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25
Q

MHC CAN BE FOUND ON WHAT CHORMOSOME?

A

CHROMOSOME 6

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26
Q

MHC LOCATION: RESTRICTED TO APC

A

CLAS 2

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27
Q

THIS MHC HAS NO LOCATION

A

CLASS 3

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28
Q

CLASS I CAN BE FOUND HIGHLY IN
:

A

LYMPHOCYTE B AND T CELL

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29
Q

CLASS 1 AN BE FOUND LOW IN

A

LIVER, NEURAL CELL, MUSCLE CELL AND SPERM

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30
Q

WHAT ARE THE GENE PRODUCT OF CLASS 1

A

HLA A
HLA B
HLA C

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31
Q

WHAT ARE THE GENE PRODUCT OF CLASS 2

A

HLA DP/SB
HLA DQ/DC
HLA DR

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32
Q

WHAT ARE THE GENE PRODUCT OF CLASS 3

A

COMPLEMENT
TNF
HEART SHOCK PROTEIN
STEROID ENZYMES

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33
Q

ROLE OF CLASS 1

A

PRESENT INTRACELLULAR ANTIGEN

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34
Q

ROLE OF CLASS 2

A

PRESENT EXTRACELLULAR ANTIGEN

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35
Q

ROLE OF CLASS 3

A

SYNTHESIS OF THEIR GENE PRODUCT

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36
Q

NO NEED FOR MHC PRESENTATION

A

B CELLS

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37
Q

MUST BE DEGRADED AND BE PRESENTED BY MHC

A

T CELLS

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38
Q

CYTOTOXIC T CELL DIRECTED AGAINST CLASS 1 ANTIGENS ARE INHIBITED BY ___

A

CD 8 CELLS

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39
Q

CYTOTOXIC T CELL DIRECTED AGAINST CLASS 2 ANTIGENS ARE INHIBITED BY __

A

CD4

40
Q

HLA ANTIGEN (HLA-B51) ASSOCIATED DISEASE

A

BEHCET

41
Q

HLA ANTIGEN (HLA-B8) ASSOCIATED DISEASE

A

CELIAC DISEASE
HIGH RESISTANCE TO HIV

42
Q

HLA ANTIGEN (HLA-B27) ASSOCIATED DISEASE

A

ANKYLOSING SPONDYLITIS

43
Q

HLA ANTIGEN (HLA-DQ2 AND DQ8) ASSOCIATED DISEASE

A

CELIAC DISEASE

44
Q

HLA ANTIGEN (HLA-DR3) ASSOCIATED DISEASE

A

JUVENILE DM/DM1., AUTOIMMUNE THYROID DISEASE

45
Q

HLA ANTIGEN (HLA-DR4) ASSOCIATED DISEASE

A

RA AND DM1

46
Q

WHAT IS THE POSITIVE AND NEGATIVE RESULT IN LYMPHOTOXICITY TEST?

A

+ DYE TAKES UP BY CELL. CELL DIE
- NO DYE TAKES UP BY CELL. CELL VIABLE

47
Q

IN MIXED LYMPHOCYTE REACTION THE DONOR LYMPHOCYTE IS __

A

STIMULATOR CELL

48
Q

IN MIXED LYMPHOYTE THE RECIPIENT LYMPHOCYTES. IS __

A

RESPONDENT CELL

49
Q

SAFEST TRANSPLANT

A

CORNEA

50
Q

PRIMARY METHOD FOR MONITORING ORGAN REJECTION OF THE HEART

A

EMDOMYOCARDIAL BIOPSU

51
Q

STANDARD MODALITY FOR TX OF AORTIC AND MITRAL VALVE

A

XENOGENIC VALVE REPLACEMENT

52
Q

USUALLY TRANSPLANTED WITH OTHER ORGAN

A

INTESTINE

53
Q

STRONGEST ASSOCIATION BETWEEN TRANSPLANT SURVIVAL ADN MOST TRANSPLANTED ORGAN

A

KIDNEY

54
Q

NO NEED FOR HLA TYPING

A

LIVER

55
Q

LARGEST. GROUP OF TRANSPLANT RECIPIENT

A

CONGENITAL BILIARY ATRESIA

56
Q

DONOR AND RECIPIENT. MUST HAVE THE SAME BRONCHIAL CIRCUMFERENCE

A

LUNGS

57
Q

WHAT ARE THE PRIMARY LYMPHOID ORGAN

A

BONE MARROW
THYMUS

58
Q

T CELLS DEELOP THEIR IDENTIFYING CHARACTERISTICS HERE

A

THYMUS

59
Q

CENTER OF ANTIGE-INDEPENDENT LYMPHOPOIESIS

A

BONE MARROW

60
Q

LARGEST. SECONDARY LYMPHOID ORGAN

A

SPLEEN

61
Q

PART OF SPLEEN WHERE YOU CAN FIND T CELLS

A

PALS

62
Q

PART OF SPLEEN WHERE YOU CAN FIND B CELLS

A

PRIMARY FOLLICLES

63
Q

PART OF SPLEEN WHERE YOU CAN FIND DENDRITIC CELLS

A

MARGINAL ZONE

64
Q

GERMINAL CENTER- PALSMA CELL
GENERATION OF B CELL IS THE PRIMARY FUNCTION

A

GALT

65
Q

RICH IN MATURE T CELLS

A

THORACIC DUCT

66
Q

MOST FREQUENT SAMPLED LYMPHOID ORGAN
MOST CIRCULATIG LYMPHOCYTES

A

BLOOD

67
Q

REFERENCE IN STANDARDIZING NAMES OF MEMBRANE PROTEINS FOUND ON ALL HUMAN WBC

A

CLUSTER OF DIFFERENTIATION

68
Q

T CELL AND NK CELL

A

CD 2

69
Q

T HELPER CELL AND MONO AND MACRO

A

CD 4

70
Q

T CYTOTOXIC AND T SUPRESSOR

A

CD 8

71
Q

most complex rbc antigen in human
second most important blood group system in terms of transfusion
can produced HDN and HTR

A

Rh

72
Q

INDIVIDUAL RBC ANTIGEN POSSESS THE D ANTIGEN

A

RH POSITIVE

73
Q

INDIVIDUAL RBC ANTIGEN LACKS OF D ANTIGEN

A

RH NEGATIVE

74
Q

PRIMARY CAUSE OF HEMOLYTIC DISEAS OF THE FETUS AND NEWBORN

A

RH ANTIBODY

75
Q

PRODUCED ONLY AFTER EXPOSURE TO FOREIGN RED CELL

A

RH ANTIBODY

76
Q

RH GENE INHERITED AS

A

CODOMINANT

77
Q

MOST COMMON RH PHENOTYPE IN BLACK

A

Dce

78
Q

MOST PROBABLE GENOTYPE IN ANY POPULATION

A

DCe/DcE

79
Q

EXPRESS IN CONMBINATION WITH BOTH C AND c AND IN TE ABSENCE OF EITHER ALLELE

A

C^W

80
Q

PRESENT. ON MOST D POSITIVE AND ALL C POSITIVE RBC

A

G

81
Q

ALSO KNOWN AS CRAWFORD ANTIGEN

A

RH43

82
Q

IMPORTANT FOR THE EXPRESSION OF RH ANTIGEN

A

RhAG gene

83
Q

3 RHAG ANTIGEN

A

RHAG 1
RHAG 2
RHAG3

84
Q

ANTIGEN PROPERTY OF RHAG

A

GLYCOPROTEIN

85
Q

FAIL TO EXPRESS ANY RH ANTIGEN ON THE RBC SURFACE
NEGATIVE LW AND FY5

A

RH NULL SYNDROME

86
Q

LESS SEVER THAN RH NULL
EXHIBIT SEVERE REDUCED EXPRESSION OF ALL RH ANTIGENS

A

RHMOD PHENOTYPE

87
Q

CHARACTERIZED BY WEAK OR ABSENT RBC AGGLUTINATION BY ANTI-D DURING ROUTINE SEROLOGIC TEST

A

WEAK D

88
Q

WEAKLY REACTIVE D MEANS A PERSON WITH D-POSITIVE?
TRUE OR FLASE

A

TRUE

89
Q

WEAK D RECIPIENTS ARE TRANSFUSED WITH ______ BLOOD

A

D NEGATIVE BLOOD

90
Q

TYPE OF RH REAGENT THAT CONTAINS IGMM ANTI D
FIRST TYPING REAGENT AVAILABLE TO TEST FOR THE D ANTIGEN

A

SALINE BASED REAGENT

91
Q

TYPE OF RH TYPING REAGENTS THAT CONSISTS OF IgG ANTI-D
HUMAN PLASMA CONTAINING HIGH TITER D-SPECIFICTY ANTIBODY WAS USED AS THE RAW MATERIAL

A

HIGH PROTEIN ANTI-D REAGENT

92
Q

TESTS FOR TEH OTHER RH ANTIGENS ARE PERFORMED WHEN IDENTIFYING UNEXPECTED RH ANTIBODIES OBTAINING COMPATIBLE BLOOD FOR A PATIENT. WITHAN RH ANTIBODY, INVESTIGATING APRENTEAGE OR OTHER FAMILY STUDIES

A

RH TYPING

93
Q

R1 MEANS

A

DCe

94
Q

RO means

A

Dce

95
Q

R2 means

A

DcE

96
Q

RZ means

A

DCE

97
Q

rY MEANS

A

dCE

ISBB (6 decks)

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