Irritable Bowel Syndrome

Question 1

What is the pertinent physiolgy of IBS?

Answer 1

multifacedted
5-HT , substance P, norepinephrine, and nitric oxide are all involved in the perception autonomic response to visceral stimulation

Question 2

How many months are minimum for chronic?

Answer 2

More than three months.

Question 3

What are the symptoms of IBS?

Answer 3

Usually begin in the late teens to twenties
abnormal stool frequency, abnormal stool form, abnormal stool passage, and bloating
HALLMARK abdominal discomfort is relieved immediately after defecation

Question 4

What are the diagnosis requirements?

Answer 4

two of the three

Relived with defecation
onset associated with a change in frequency of stool
onset associated with a change in form of stool

Question 5

What are the three major classifications of IBS?

Answer 5

IBS-C IBS with constipation
IBS-D IBS with diarrhea
IBS-U Infrequent bowel movements
or IBS M Mixed constipation and diarrhea

Question 6

What are some of the alarm symptoms for IBS?

Answer 6

Acute onset of symptoms in patients between forty and fifty years of age
nocturnal diarrhea
severe constipation
hematozhezia
Weight loss
fever
family hsitory of cancer, inflammatory bowel disease, or celiac disease

Question 7

What are the physical exam findings?

Answer 7

Usually normal should not have associated fevers, rashed, blood in stool
abdominal tendernesss, ispecially in the lower abdomen is common, but not pronounced

Question 8

What is the symtpomatic treatment medication for IBS?

Answer 8

Methscoplolamine 2.5-5mg orally before meals and at bedtime
Hyoscyamine .125 mg orally
Diccolimine 10-20 mg PO quid