Irritable Bowel Disease (Week 4 GI) Flashcards
What is IBS?
A chronic disorder characterized by abdominal pain or discomfort associated with disordered defecation.
When does a person receive formal evaluation for IBS?
Symptoms ongoing at least 6 months beforehand
What is the diagnostic criteria for IBS?
Must include both of the following
1). Abdominal discomfort or pain should be present at least 3 days per months for 3 months and should be associated with 2 or more of the following at least 25% of the time
* Improvement with defecation
* Onset associated with change in stool frequency of stool.
* Onset associated with a change in form (appearance) of stool.
2). No evidence of inflammatory, anatomic, metabolic, or neoplastic process that explains the patient’s symptoms
* rule out ohter diseases
3). Phenotypic expressions:
* diarrhea predominant
* constipation predominant
* or mixed.
IBS cause
unknown
IBS prevalence
10-30% (US, Canada)
* largest ambulatory problem in adults and children, can be very painful but difficult to solve
What are some associations with IBS?
- ↓ fibre and ↑ refined CHO intake
- prolonged bowel transit time
- stressful lifestyle
- irregular eating/ bowel habits
- laxative abuse
pathophysiology of IBS
CRH = cortico-tropin releasing hormone
What are some nutritional factors in the pathogenesis of IBS?
Adverse reactions to specific types of foods
* most common: alcohol, caffeine containing beverages and foods (chocolate, coffee) → potential efficacy of elimination diets.
* gluten intolerance (conflicting evidence) → some may have CD some may have non-CD gluten intolerance
* potential lactose intolerance
* potential fructose malabsorption
* potential others: fatty foods, high in simple sugars, spices
Individual variation
What is the purpose of nutrition care for IBS?
- To prevent or minimize gastrointestinal symptoms
- To promote normal bowel function
What is the nutrition care for IBS?
- Integration with other factors
- fibre therapy
- small frequent meals
- relaxed eating environment
What other factors should nutrition care for IBS be integrated with?
- stress management: increase cortisol can lead to further inflammation
- drug therapy: consider potential GI side effects, herbal remedy use
- lifestyle modications: bowel habits and acitivity, variable amoung individuals
- elimination of irritants identifed by patient
How is fibre therapy used for IBS?
- start on low dose of fibre and increase gradually to 15-25-35 g/d usually with diet bran or psyllium (controversy)
- reduce simple CHO and sugar alcohols (FODMAP diets)
monitor results and ensure adequate fluid
What does FODMAP stand for?
- Fermentable
- Oligo-,
- Di-, and
- Monosaccharides
- And
- Polyols
What are FODMAPS?
Group of short chain CHO that share common features
* rapidly absorbed in the SI
* rapidly fermented by colonic bacteria
* increase water delivery into the bowel due to their high osmolarity
What are common potential FODMAPS? and there
* physiological effects?
* common symptoms?
- potential FODMAPS: lactose, fructans, polyols, excess fructose, GOS
- physiological effects: gas production, water delivery to lumen, luminal distention
- common symptoms: excess flatus, abdominal pain, abdominal bloating, altered bowel motility