Irreversible MAO-I (MAO-A and MAO-B) Flashcards

1
Q

phenelzine (Nardil)

A

Irreversible MAO-I

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2
Q

tranylcypromine (Parnate)

A

Irreversible MAO-I

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3
Q

All Irreversible MAO inhibitors

A
  • dysthymic disorder, atypical depression, SAD, bipolar depression, MEDICATION REFRACTORY DEPRESSION
  • increase NE and 5HT
  • downregulation of receptors

SE: insomnia, hypotension, weight gain, tyramine reaction (release of NE causes hypertension), serotonin syndrome

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