Irreversible MAO-I (MAO-A and MAO-B) Flashcards
1
Q
phenelzine (Nardil)
A
Irreversible MAO-I
2
Q
tranylcypromine (Parnate)
A
Irreversible MAO-I
3
Q
All Irreversible MAO inhibitors
A
- dysthymic disorder, atypical depression, SAD, bipolar depression, MEDICATION REFRACTORY DEPRESSION
- increase NE and 5HT
- downregulation of receptors
SE: insomnia, hypotension, weight gain, tyramine reaction (release of NE causes hypertension), serotonin syndrome