Iron deficiency and iron-deficiency anaemia in women’s health 2017 TOG– Flashcards
What is the most common micronutrient deficiency worldwide?
Iron deficiency
What proportion of women are iron deficiency in their reproductive years
20%
Non pregnancy definition of anaemia
↓120 g/l
What is Hepcidin?
25-amino acid peptide hormone that regulates iron uptake and release from stores in response to circulating and tissue levels of iron.
Ferric iron (Fe2+) and ferrous iron (Fe3+), which iron is better absorbed from the guy
Ferric iron FE2+
For every ml of blood lost, how much iron is lost?
0.5mg
A daily loss >5mg, exceeds body compensatory mechanism to increase iron absorption, reducing iron supple.
Causes of iron deficiency diagram
What proportion of of women with HMB bleeding are iron deficient
63%
Worldwide HMB account for what probation of iron deficiency?
20-30%
Causes of HMB
PALM-COEIN
Haemoglobin levels in non-pregnancy, pregnant, men
Investigations for iron deficiency and iron deficiency anaemia
- Hb
- Serum ferritin
- Transferrin Conc
- Soluble transferrin receptor
Ferritin < 15 - iron deficiency
For iron deficiency how much elemental iron should be taken?
100-200mg
Iron consent of oral iron preparations
- Ferrous fumate/sulphate
To maximise absorbtion of iron when should it be taken
At night or 1 hour before food
Do not take with tannins and milk
Ascorbic acid in fruit juice increase uptake
