Hormone replacement therapy following gynaecological malignancies TOG 2019

Question 1

What proportion of women with a gynaecological malignancy are pre or perimenopausal?

Answer 1

30-40%

Question 2

Which gynae cancers can have HRT?

Answer 2

Type 1 Endometrial cance, stage 1 & 2,
Cervical squamous cell stage 1 & 2
Vaginal/vuvlal squamous cell

For all if hysterectomy can have estrogen only, otherwise combined

Question 3

Which gynaecological cancer is most common in UK?

Answer 3

Endometrial cancer

Question 4

What is type 1 endometrial cancer?

Answer 4

Estrogen-dependent (majority)

Question 5

3 most common types of ovarian cancer

Answer 5

Epithelial ovarian cancer 90%
Germ call tumour 5%
Sex cord stromal 1.2%

Question 6

What age group does germ cell tumour most commonly effect?

Answer 6

Age 10-30years

Question 7

What age group does sex cord stromal tumours present?

Answer 7

60% 30-59
12% < 30

Question 8

Highest incidence of cervical cancer?

Answer 8

25-29yrs

Question 9

Most common type of vulval cancer?

Answer 9

Non-estrogen dependant SCC