ION CHANNELS AND TOXINS Flashcards

1
Q

Sodium Channel

A

Tetrodotoxin
Batrachotoxin (BTX)

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2
Q

Potassium Channel

A

Apamin
Charybdotoxin

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3
Q

Calcium Channel

A

Omega-conotoxin
Agatoxin

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4
Q

Nicotinic Ach Receptor

A

a-Bungarotoxin

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5
Q

GABAA Receptor

A

Pictrotoxin

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6
Q

Glycine Receptor

A

Strychnine

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7
Q

AMPA Receptor

A

Philanthotoxin

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8
Q

Blocks sodium channel from outside

A

Tetrodotoxin

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9
Q

Slows sodium channel inactivation; shifts activation

A

Batrachotoxin

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10
Q

Source: Puffer fish

A

Tetrodotoxin

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11
Q

Source: Colombian frog

A

Batrachotoxin

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12
Q

Blocks small Ca-activated K receptors

A

Apamin

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13
Q

Blocks big Ca-activated K receptors

A

Charybdotoxin

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14
Q

Source: Honeybee

A

Apamin

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15
Q

Source: Scorpion

A

Charybdotoxin

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16
Q

Blocks N-type calcium channel

A

Omega conotoxin

17
Q

Blocks P-type calcium channel

A

Agatoxin

18
Q

Source: Pacific Cone Snail

A

Omega conotoxin

19
Q

Source: Funnel Web Spider

A

Agatoxin

20
Q

Irreversible antagonist

A

a-Bungarotoxin

21
Q

Source: Marine snake

A

a-Bungarotoxin

22
Q

Blocks GABAA channel

A

Pictrotoxin

23
Q

Source: South Pacific Plant

A

Pictrotoxin

24
Q

Competitive glycine antagonist

A

Strychnine

25
Q

Source: Indian plant

A

Strychnine

26
Q

Blocks AMPA channel

A

Philanthotoxin

27
Q

Source: Wasp

A

Philanthotoxin